RAB234_Nonuc_Trpn_vs_Trpp_RNAseq_report

Introduction

Data from RAB : CD8+ T cells from mice

• Cell types: not nucleofected, scramble, Nduf KO, Mrpl28 KO

• Conditions: treated w/ or w/o Tryptophan

• Biological replicates (3)

Volcano plot

Getting some stats yay

table(res_tbl$padj<=0.05) # significant genes

## 
## FALSE  TRUE 
## 10762  7486

table(res_tbl$padj<=0.05&res_tbl$log2FoldChange<=-1) # signif and downreg

## 
## FALSE  TRUE 
## 21299  2119

table(res_tbl$padj<=0.05&res_tbl$log2FoldChange>=1) # signif and upreg

## 
## FALSE  TRUE 
## 23240   967

GSEA analysis logFc

Gene ontology

ID	setSize	enrichmentScore	NES	pvalue	p.adjust	qvalue
GOBP_RIBOSOME_BIOGENESIS	188	0.4202304	2.262517	0.0000000	0.0000001	0.0000001
GOBP_NCRNA_PROCESSING	219	0.3982346	2.140165	0.0000000	0.0000001	0.0000001
GOBP_RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS	243	0.3702549	2.033228	0.0000000	0.0000003	0.0000002
GOBP_NCRNA_METABOLIC_PROCESS	291	0.3330353	1.869525	0.0000000	0.0000027	0.0000025
GOBP_RRNA_METABOLIC_PROCESS	165	0.3546795	1.873524	0.0000006	0.0003758	0.0003423
GOBP_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS	367	-0.4190080	-1.593634	0.0000010	0.0005444	0.0004958
GOBP_SECOND_MESSENGER_MEDIATED_SIGNALING	104	-0.5317041	-1.877538	0.0000030	0.0014366	0.0013084
GOBP_MITOCHONDRIAL_GENE_EXPRESSION	60	0.4937235	2.205917	0.0000051	0.0021201	0.0019310
GOBP_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS	424	-0.3978751	-1.518565	0.0000073	0.0026851	0.0024456
GOBP_REGULATION_OF_BLOOD_CIRCULATION	81	-0.5507294	-1.893945	0.0000120	0.0039641	0.0036105
GOBP_NUCLEOSOME_ASSEMBLY	42	-0.6308289	-1.983763	0.0000185	0.0055704	0.0050735
GOBP_CIRCULATORY_SYSTEM_PROCESS	192	-0.4542605	-1.684249	0.0000273	0.0070828	0.0064510
GOBP_CELL_JUNCTION_ORGANIZATION	250	-0.4234105	-1.590739	0.0000278	0.0070828	0.0064510
GOBP_BLOOD_VESSEL_MORPHOGENESIS	234	-0.4274936	-1.602745	0.0000389	0.0092077	0.0083863
GOBP_EPITHELIUM_DEVELOPMENT	396	-0.3905801	-1.488672	0.0000430	0.0094832	0.0086372
GOBP_TUBE_MORPHOGENESIS	327	-0.4078165	-1.545576	0.0000505	0.0100062	0.0091136
GOBP_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT	415	-0.3873085	-1.477693	0.0000514	0.0100062	0.0091136
GOBP_MITOCHONDRIAL_TRANSLATION	40	0.5425012	2.223763	0.0000764	0.0140421	0.0127895
GOBP_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_SIGNALING_PATHWAY	12	-0.7962391	-1.928079	0.0000948	0.0160636	0.0146306
GOBP_METAL_ION_TRANSPORT	287	-0.4093355	-1.546197	0.0000971	0.0160636	0.0146306
GOBP_DNA_REPLICATION_DEPENDENT_CHROMATIN_ORGANIZATION	12	-0.7929755	-1.920176	0.0001171	0.0161505	0.0147099
GOBP_CELLULAR_RESPONSE_TO_CORTICOSTEROID_STIMULUS	18	-0.7201209	-1.911504	0.0001123	0.0161505	0.0147099
GOBP_NUCLEOSOME_ORGANIZATION	68	-0.5441418	-1.832523	0.0001058	0.0161505	0.0147099
GOBP_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION	108	-0.4916194	-1.742060	0.0001163	0.0161505	0.0147099
GOBP_VASCULATURE_DEVELOPMENT	273	-0.4057025	-1.530667	0.0001222	0.0161831	0.0147395
GOBP_TRNA_METABOLIC_PROCESS	94	0.3826494	1.851779	0.0001406	0.0166234	0.0151405
GOBP_REGULATION_OF_HEART_CONTRACTION	68	-0.5408257	-1.821355	0.0001337	0.0166234	0.0151405
GOBP_HEART_PROCESS	83	-0.5190101	-1.789866	0.0001452	0.0166234	0.0151405
GOBP_REGULATION_OF_SYSTEM_PROCESS	169	-0.4429369	-1.628337	0.0001511	0.0166234	0.0151405
GOBP_REGULATION_OF_ION_TRANSPORT	209	-0.4320044	-1.611367	0.0001557	0.0166234	0.0151405
GOBP_TISSUE_MORPHOGENESIS	224	-0.4202805	-1.572373	0.0001554	0.0166234	0.0151405
GOBP_NEGATIVE_REGULATION_OF_LOCOMOTION	126	-0.4692152	-1.687861	0.0001808	0.0184509	0.0168050
GOBP_TUBE_DEVELOPMENT	395	-0.3777990	-1.439766	0.0001895	0.0184509	0.0168050
GOBP_CIRCULATORY_SYSTEM_DEVELOPMENT	404	-0.3739173	-1.425661	0.0001873	0.0184509	0.0168050
GOBP_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY	218	-0.4185485	-1.563937	0.0001968	0.0186101	0.0169500
GOBP_MULTI_MULTICELLULAR_ORGANISM_PROCESS	78	-0.5151214	-1.764197	0.0002062	0.0189635	0.0172719
GOBP_SECONDARY_ALCOHOL_METABOLIC_PROCESS	73	-0.5294475	-1.797978	0.0002358	0.0210972	0.0192152
GOBP_REGULATION_OF_MULTICELLULAR_ORGANISMAL_DEVELOPMENT	500	-0.3658697	-1.400679	0.0002576	0.0224403	0.0204386
GOBP_TRNA_PROCESSING	59	0.4332874	1.930042	0.0002668	0.0226412	0.0206216
GOBP_DIVALENT_INORGANIC_CATION_HOMEOSTASIS	176	-0.4360282	-1.608350	0.0002741	0.0226811	0.0206578
GOBP_RESPONSE_TO_WOUNDING	218	-0.4146453	-1.549352	0.0002937	0.0237143	0.0215989
GOBP_NEGATIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY	12	-0.7721924	-1.869851	0.0003058	0.0241009	0.0219510
GOBP_PEPTIDE_ANTIGEN_ASSEMBLY_WITH_MHC_PROTEIN_COMPLEX	10	-0.7995064	-1.850430	0.0003191	0.0244478	0.0222670
GOBP_SYNAPSE_ORGANIZATION	145	-0.4407451	-1.606583	0.0003250	0.0244478	0.0222670
GOBP_NON_MOTILE_CILIUM_ASSEMBLY	27	0.5591436	2.075650	0.0003576	0.0251526	0.0229089
GOBP_PROTEIN_LOCALIZATION_TO_CELL_SURFACE	30	0.5351167	2.036139	0.0003648	0.0251526	0.0229089
GOBP_REGULATION_OF_VASOCONSTRICTION	17	-0.7320425	-1.924947	0.0003637	0.0251526	0.0229089
GOBP_RESPONSE_TO_BACTERIUM	196	-0.4202941	-1.560183	0.0003516	0.0251526	0.0229089
GOBP_EPITHELIAL_CELL_DIFFERENTIATION	212	-0.4160709	-1.552853	0.0003869	0.0261372	0.0238057
GOBP_INFLAMMATORY_RESPONSE	269	-0.3985508	-1.502971	0.0004386	0.0290328	0.0264430
GOBP_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION	42	-0.5841990	-1.837126	0.0004654	0.0301290	0.0274414
GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION	62	-0.5179816	-1.721081	0.0004733	0.0301290	0.0274414
GOBP_REGULATION_OF_TRANS_SYNAPTIC_SIGNALING	130	-0.4444338	-1.602743	0.0005254	0.0328112	0.0298843
GOBP_REGULATION_OF_HYDROLASE_ACTIVITY	413	-0.3658946	-1.395743	0.0005546	0.0339923	0.0309601
GOBP_AMINO_ACID_ACTIVATION	26	0.5691117	2.091506	0.0005724	0.0344476	0.0313748
GOBP_REGULATION_OF_BLOOD_PRESSURE	51	-0.5560272	-1.800739	0.0006133	0.0362496	0.0330160
GOBP_POSITIVE_CHEMOTAXIS	21	-0.6654548	-1.831806	0.0006533	0.0379392	0.0345549
GOBP_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT	56	-0.5393640	-1.770717	0.0006891	0.0393287	0.0358204
GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION	55	-0.5290421	-1.732068	0.0007336	0.0404695	0.0368595
GOBP_REGULATION_OF_METAL_ION_TRANSPORT	134	-0.4443028	-1.606388	0.0007264	0.0404695	0.0368595
GOBP_CATION_TRANSPORT	386	-0.3715800	-1.414838	0.0007476	0.0405689	0.0369500
GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN	32	-0.6078114	-1.819012	0.0007662	0.0407760	0.0371386
GOBP_RNA_MODIFICATION	81	0.3737751	1.768056	0.0007761	0.0407760	0.0371386
GOBP_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS	20	-0.6710952	-1.828484	0.0008721	0.0451026	0.0410793
GOBP_POSITIVE_REGULATION_OF_VASOCONSTRICTION	11	-0.7703247	-1.829313	0.0009319	0.0474542	0.0432211

Reactome

ID	setSize	enrichmentScore	NES	pvalue	p.adjust	qvalue
REACTOME_METABOLISM_OF_RNA	354	0.3181325	1.790770	0.0000000	0.0000001	0.0000001
REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION	19	-0.8248996	-2.234797	0.0000000	0.0000145	0.0000121
REACTOME_DNA_DAMAGE_TELOMERE_STRESS_INDUCED_SENESCENCE	27	-0.7525998	-2.187419	0.0000002	0.0000387	0.0000324
REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3	17	-0.8218206	-2.175183	0.0000002	0.0000387	0.0000324
REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA	22	-0.7783629	-2.174067	0.0000002	0.0000387	0.0000324
REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION	18	-0.8077241	-2.163898	0.0000004	0.0000412	0.0000344
REACTOME_RRNA_PROCESSING	121	0.4167129	2.125377	0.0000003	0.0000412	0.0000344
REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION	17	-0.8106785	-2.145692	0.0000006	0.0000635	0.0000531
REACTOME_HDACS_DEACETYLATE_HISTONES	20	-0.7848922	-2.148112	0.0000009	0.0000808	0.0000675
REACTOME_GPCR_LIGAND_BINDING	85	-0.5701547	-1.973017	0.0000012	0.0001004	0.0000840
REACTOME_RHO_GTPASES_ACTIVATE_PKNS	32	-0.6900298	-2.070302	0.0000051	0.0003743	0.0003129
REACTOME_RESPONSE_OF_EIF2AK1_HRI_TO_HEME_DEFICIENCY	14	0.7983226	2.450254	0.0000062	0.0004164	0.0003481
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	32	-0.6855547	-2.056876	0.0000075	0.0004658	0.0003893
REACTOME_DNA_METHYLATION	18	-0.7702184	-2.063420	0.0000082	0.0004758	0.0003977
REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES	23	-0.7373536	-2.078302	0.0000134	0.0007266	0.0006073
REACTOME_RMTS_METHYLATE_HISTONE_ARGININES	30	-0.6846354	-2.030726	0.0000207	0.0009769	0.0008165
REACTOME_HDMS_DEMETHYLATE_HISTONES	18	-0.7574607	-2.029242	0.0000193	0.0009769	0.0008165
REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	61	-0.5784696	-1.920470	0.0000224	0.0009769	0.0008165
REACTOME_TRANSLATION	150	0.3394148	1.783755	0.0000229	0.0009769	0.0008165
REACTOME_MUSCLE_CONTRACTION	64	-0.5667502	-1.894519	0.0000285	0.0011564	0.0009666
REACTOME_AMYLOID_FIBER_FORMATION	26	-0.6948552	-2.005490	0.0000326	0.0012382	0.0010350
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	93	-0.5228802	-1.829064	0.0000336	0.0012382	0.0010350
REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES	16	-0.7692750	-2.012026	0.0000384	0.0013557	0.0011332
REACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL	42	0.5146336	2.117212	0.0000494	0.0016676	0.0013939
REACTOME_MITOCHONDRIAL_TRANSLATION	47	0.5030006	2.136305	0.0000627	0.0018825	0.0015735
REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION	31	-0.6612151	-1.973243	0.0000649	0.0018825	0.0015735
REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION	36	-0.6362680	-1.951250	0.0000650	0.0018825	0.0015735
REACTOME_SIGNALING_BY_GPCR	203	-0.4393624	-1.633643	0.0000648	0.0018825	0.0015735
REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION	28	-0.6718228	-1.966916	0.0000731	0.0019767	0.0016523
REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE	29	-0.6660953	-1.963595	0.0000727	0.0019767	0.0016523
REACTOME_RECOGNITION_AND_ASSOCIATION_OF_DNA_GLYCOSYLASE_WITH_SITE_CONTAINING_AN_AFFECTED_PURINE	15	-0.7763891	-2.001794	0.0000823	0.0021527	0.0017994
REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	28	-0.6672434	-1.953509	0.0000887	0.0022490	0.0018798
REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS	34	-0.6399327	-1.937420	0.0001100	0.0027045	0.0022607
REACTOME_INHIBITION_OF_DNA_RECOMBINATION_AT_TELOMERE	15	-0.7681219	-1.980479	0.0001223	0.0028333	0.0023683
REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION	37	-0.6102480	-1.880198	0.0001221	0.0028333	0.0023683
REACTOME_MEIOTIC_RECOMBINATION	27	-0.6678077	-1.940973	0.0001363	0.0030700	0.0025662
REACTOME_HCMV_LATE_EVENTS	41	-0.6030408	-1.886807	0.0001451	0.0031799	0.0026580
REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION	36	-0.6167328	-1.891342	0.0001911	0.0040778	0.0034085
REACTOME_GENE_SILENCING_BY_RNA	48	-0.5831423	-1.871125	0.0002346	0.0048778	0.0040772
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS	29	-0.6397653	-1.885976	0.0002679	0.0054326	0.0045410
REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH	35	-0.6211771	-1.893189	0.0003365	0.0062022	0.0051843
REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX	30	-0.6357073	-1.885598	0.0003257	0.0062022	0.0051843
REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE	11	-0.7835626	-1.875487	0.0003243	0.0062022	0.0051843
REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION	50	-0.5619663	-1.815751	0.0003361	0.0062022	0.0051843
REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS	36	-0.6035609	-1.850947	0.0003951	0.0071200	0.0059515
REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES	33	-0.6155661	-1.854636	0.0004474	0.0078871	0.0065926
REACTOME_CHOLESTEROL_BIOSYNTHESIS	20	-0.6912764	-1.891902	0.0004918	0.0084513	0.0070642
REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE	50	-0.5527892	-1.786099	0.0005002	0.0084513	0.0070642
REACTOME_PERK_REGULATES_GENE_EXPRESSION	20	0.6152588	2.108650	0.0005879	0.0097310	0.0081339
REACTOME_BASE_EXCISION_REPAIR_AP_SITE_FORMATION	20	-0.6858669	-1.877097	0.0006064	0.0098359	0.0082215
REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF	36	-0.5902649	-1.810172	0.0006608	0.0105077	0.0087831
REACTOME_INTERFERON_ALPHA_BETA_SIGNALING	32	-0.6010899	-1.803455	0.0007744	0.0120782	0.0100959
REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP	33	-0.5988184	-1.804177	0.0009783	0.0149697	0.0125128
REACTOME_TRANSCRIPTION_OF_THE_HIV_GENOME	30	0.5140065	1.941619	0.0010491	0.0157562	0.0131703
REACTOME_HCMV_EARLY_EVENTS	52	-0.5435194	-1.767743	0.0012862	0.0183634	0.0153495
REACTOME_MEIOSIS	44	-0.5566760	-1.762579	0.0012739	0.0183634	0.0153495
REACTOME_REPRODUCTION	50	-0.5353868	-1.729871	0.0012936	0.0183634	0.0153495
REACTOME_CELLULAR_SENESCENCE	84	-0.4845548	-1.674394	0.0013133	0.0183634	0.0153495
REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	101	-0.4656461	-1.642276	0.0013665	0.0187843	0.0157013
REACTOME_DECTIN_1_MEDIATED_NONCANONICAL_NF_KB_SIGNALING	41	0.4483596	1.830044	0.0015701	0.0208744	0.0174484
REACTOME_FORMATION_OF_SENESCENCE_ASSOCIATED_HETEROCHROMATIN_FOCI_SAHF	12	-0.7418583	-1.810833	0.0015531	0.0208744	0.0174484
REACTOME_TRNA_AMINOACYLATION	23	0.5581536	1.986800	0.0016949	0.0218595	0.0182718
REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	52	0.4322670	1.873402	0.0016981	0.0218595	0.0182718
REACTOME_HIV_TRANSCRIPTION_INITIATION	22	0.5588907	1.971723	0.0022967	0.0291037	0.0243270
REACTOME_NGF_STIMULATED_TRANSCRIPTION	22	-0.6273514	-1.752272	0.0024905	0.0299532	0.0250371
REACTOME_NONHOMOLOGOUS_END_JOINING_NHEJ	24	-0.6146130	-1.747632	0.0024522	0.0299532	0.0250371
REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS	26	-0.6040087	-1.743289	0.0025484	0.0299532	0.0250371
REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP	37	-0.5597393	-1.724579	0.0025399	0.0299532	0.0250371
REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL	38	-0.5549380	-1.716007	0.0025347	0.0299532	0.0250371
REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES	91	-0.4586302	-1.600197	0.0029161	0.0337849	0.0282399
REACTOME_DEFECTIVE_CFTR_CAUSES_CYSTIC_FIBROSIS	40	0.4386227	1.779165	0.0031385	0.0348966	0.0291692
REACTOME_HCMV_INFECTION	67	-0.4899399	-1.645919	0.0031411	0.0348966	0.0291692
REACTOME_ESR_MEDIATED_SIGNALING	82	-0.4714735	-1.624109	0.0030611	0.0348966	0.0291692
REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE	24	-0.6078438	-1.728384	0.0032266	0.0349151	0.0291847
REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING	41	-0.5491890	-1.718314	0.0032289	0.0349151	0.0291847
REACTOME_ABC_TRANSPORTER_DISORDERS	43	0.4301494	1.780849	0.0033251	0.0353239	0.0295264
REACTOME_MRNA_SPLICING	93	0.3208986	1.557679	0.0033538	0.0353239	0.0295264
REACTOME_ATF4_ACTIVATES_GENES_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS	17	0.6043709	1.969259	0.0034389	0.0357555	0.0298872
REACTOME_CELL_CELL_JUNCTION_ORGANIZATION	17	-0.6670013	-1.765410	0.0036462	0.0362784	0.0303242
REACTOME_SWITCHING_OF_ORIGINS_TO_A_POST_REPLICATIVE_STATE	47	0.4047876	1.719183	0.0035756	0.0362784	0.0303242
REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR	51	0.3967764	1.717372	0.0036149	0.0362784	0.0303242
REACTOME_MEIOTIC_SYNAPSIS	27	-0.5882600	-1.709769	0.0036681	0.0362784	0.0303242
REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	43	-0.5400266	-1.702675	0.0038014	0.0371436	0.0310474
REACTOME_REGULATION_OF_HMOX1_EXPRESSION_AND_ACTIVITY	41	0.4253605	1.736170	0.0042169	0.0407127	0.0340308
REACTOME_ORC1_REMOVAL_FROM_CHROMATIN	38	0.4375405	1.751806	0.0042945	0.0409744	0.0342495
REACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX	18	0.5696858	1.893476	0.0047252	0.0435466	0.0363996
REACTOME_HATS_ACETYLATE_HISTONES	57	-0.4971303	-1.636556	0.0046830	0.0435466	0.0363996
REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	60	-0.4898048	-1.622921	0.0046617	0.0435466	0.0363996
REACTOME_O_LINKED_GLYCOSYLATION	26	-0.5833032	-1.683528	0.0048420	0.0436318	0.0364707
REACTOME_CARDIAC_CONDUCTION	38	-0.5431413	-1.679529	0.0048280	0.0436318	0.0364707
REACTOME_REGULATION_OF_PTEN_STABILITY_AND_ACTIVITY	38	0.4325294	1.731743	0.0050413	0.0449289	0.0375549
REACTOME_TRNA_PROCESSING	52	0.4030996	1.746994	0.0052215	0.0450492	0.0376555
REACTOME_DNA_DOUBLE_STRAND_BREAK_RESPONSE	32	-0.5570441	-1.671305	0.0051839	0.0450492	0.0376555
REACTOME_METABOLISM_OF_STEROIDS	62	-0.4851718	-1.613509	0.0052207	0.0450492	0.0376555
REACTOME_MITOTIC_PROPHASE	62	-0.4815711	-1.601535	0.0057882	0.0494131	0.0413032

Wikipathways

ID	setSize	enrichmentScore	NES	pvalue	p.adjust	qvalue
WP_CHOLESTEROL_BIOSYNTHESIS_PATHWAY	15	-0.7699181	-1.974693	0.0000848	0.0234200	0.0221688
WP_CHOLESTEROL_METABOLISM_WITH_BLOCH_AND_KANDUTSCHRUSSELL_PATHWAYS	36	-0.6274836	-1.926183	0.0001180	0.0234200	0.0221688
WP_NRF2ARE_REGULATION	12	0.7253024	2.225841	0.0003877	0.0317013	0.0300076
WP_HIPPO_SIGNALING_REGULATION_PATHWAYS	37	-0.6083571	-1.868926	0.0003036	0.0317013	0.0300076
WP_HIPPOMERLIN_SIGNALING_DYSREGULATION	48	-0.5738623	-1.846478	0.0003993	0.0317013	0.0300076
WP_GENES_RELATED_TO_PRIMARY_CILIUM_DEVELOPMENT_BASED_ON_CRISPR	56	0.4202437	1.922558	0.0007543	0.0455173	0.0430854
WP_NETWORK_MAP_OF_SARSCOV2_SIGNALING_PATHWAY	95	-0.4818131	-1.688382	0.0008026	0.0455173	0.0430854

Perturbations

ID	setSize	enrichmentScore	NES	pvalue	p.adjust	font.size
MARTENS_TRETINOIN_RESPONSE_UP	184	-0.5872224	-2.159815	0.0e+00	0.0000001	0.0000001
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	374	-0.5034767	-1.907819	0.0e+00	0.0000001	0.0000001
QI_HYPOXIA	91	-0.5949457	-2.063067	0.0e+00	0.0000144	0.0000123
MEBARKI_HCC_PROGENITOR_FZD8CRD_DN	129	-0.5518763	-1.990844	0.0e+00	0.0000144	0.0000123
MIKKELSEN_MEF_HCP_WITH_H3K27ME3	103	-0.5776911	-2.041288	0.0e+00	0.0000223	0.0000190
ELVIDGE_HIF1A_TARGETS_DN	59	-0.6431329	-2.103057	1.0e-07	0.0000411	0.0000351
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP	60	-0.6245174	-2.044445	3.0e-07	0.0000926	0.0000791
GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN	13	0.8460883	2.553701	3.0e-07	0.0000935	0.0000799
ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN	65	-0.6113137	-2.025274	7.0e-07	0.0001710	0.0001461
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP	66	-0.6091698	-2.020585	9.0e-07	0.0001851	0.0001581
ELVIDGE_HYPOXIA_UP	95	-0.5558713	-1.936141	1.1e-06	0.0001851	0.0001581
MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED	170	-0.4946995	-1.811719	9.0e-07	0.0001851	0.0001581
LINDGREN_BLADDER_CANCER_CLUSTER_2B	167	-0.4893748	-1.788294	1.0e-06	0.0001851	0.0001581
BENPORATH_ES_WITH_H3K27ME3	241	-0.4548713	-1.693899	1.1e-06	0.0001851	0.0001581
BLANCO_MELO_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_A594_CELLS_UP	122	-0.5267929	-1.890439	1.2e-06	0.0001909	0.0001630

Hallmarks

ID	setSize	enrichmentScore	NES	pvalue	p.adjust	qvalue
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	64	0.4383292	2.004361	0.0001087	0.0047896	0.0036300
HALLMARK_COAGULATION	41	-0.6079492	-1.896209	0.0001916	0.0047896	0.0036300
HALLMARK_KRAS_SIGNALING_DN	48	-0.5567782	-1.776552	0.0005328	0.0066598	0.0050474
HALLMARK_MYOGENESIS	83	-0.5012911	-1.724630	0.0004401	0.0066598	0.0050474
HALLMARK_MYC_TARGETS_V1	111	0.3269211	1.626157	0.0012892	0.0128916	0.0097705
HALLMARK_CHOLESTEROL_HOMEOSTASIS	48	-0.5304719	-1.692615	0.0022801	0.0176641	0.0133876
HALLMARK_ESTROGEN_RESPONSE_EARLY	98	-0.4475800	-1.578372	0.0024730	0.0176641	0.0133876
HALLMARK_ESTROGEN_RESPONSE_LATE	91	-0.4571878	-1.590534	0.0047591	0.0297441	0.0225429
HALLMARK_KRAS_SIGNALING_UP	79	-0.4671946	-1.605742	0.0062644	0.0348024	0.0263766

GSEA analysis pvalue

Gene ontology

Reactome

Wikipathways

Perturbations

Hallmarks

ORA

GOBP

ID	GeneRatio	p.adjust	qvalue
GOBP_STEROL_METABOLIC_PROCESS	48/2195	0.0000846	0.0000754
GOBP_AXON_DEVELOPMENT	108/2195	0.0001624	0.0001448
GOBP_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION	111/2195	0.0001624	0.0001448
GOBP_SECONDARY_ALCOHOL_METABOLIC_PROCESS	45/2195	0.0001624	0.0001448
GOBP_STEROL_BIOSYNTHETIC_PROCESS	25/2195	0.0002127	0.0001897
GOBP_MONONUCLEAR_CELL_DIFFERENTIATION	98/2195	0.0002714	0.0002420
GOBP_POSITIVE_REGULATION_OF_CELL_ADHESION	98/2195	0.0005136	0.0004579
GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION	59/2195	0.0012264	0.0010935
GOBP_REGULATION_OF_CELL_CELL_ADHESION	97/2195	0.0012264	0.0010935
GOBP_ALCOHOL_METABOLIC_PROCESS	79/2195	0.0012264	0.0010935
GOBP_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION	67/2195	0.0012264	0.0010935
GOBP_CELL_ADHESION_MEDIATED_BY_INTEGRIN	29/2195	0.0012264	0.0010935
GOBP_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	70/2195	0.0013574	0.0012102
GOBP_VASCULAR_TRANSPORT	29/2195	0.0017692	0.0015774
GOBP_T_CELL_ACTIVATION	103/2195	0.0017908	0.0015966
GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE	25/2195	0.0018220	0.0016245
GOBP_ORGANIC_HYDROXY_COMPOUND_BIOSYNTHETIC_PROCESS	58/2195	0.0024443	0.0021792
GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION	30/2195	0.0025069	0.0022351
GOBP_WOUND_HEALING	91/2195	0.0025209	0.0022476
GOBP_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY	46/2195	0.0041020	0.0036572
GOBP_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION	68/2195	0.0041020	0.0036572
GOBP_LEUKOCYTE_CELL_CELL_ADHESION	80/2195	0.0042734	0.0038101
GOBP_RAS_PROTEIN_SIGNAL_TRANSDUCTION	76/2195	0.0043562	0.0038838
GOBP_LEUKOTRIENE_BIOSYNTHETIC_PROCESS	9/2195	0.0092092	0.0082107
GOBP_NEGATIVE_REGULATION_OF_LOCOMOTION	70/2195	0.0092092	0.0082107
GOBP_RESPONSE_TO_METAL_ION	74/2195	0.0092092	0.0082107
GOBP_NEURON_PROJECTION_GUIDANCE	55/2195	0.0112181	0.0100017
GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_EXOGENOUS_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_II	11/2195	0.0112574	0.0100368
GOBP_AMEBOIDAL_TYPE_CELL_MIGRATION	86/2195	0.0140645	0.0125395
GOBP_CARBOHYDRATE_CATABOLIC_PROCESS	38/2195	0.0140645	0.0125395
GOBP_PHOSPHOLIPID_METABOLIC_PROCESS	80/2195	0.0140645	0.0125395
GOBP_SMOOTH_MUSCLE_CELL_MIGRATION	22/2195	0.0140645	0.0125395
GOBP_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE	31/2195	0.0140645	0.0125395
GOBP_STEROID_METABOLIC_PROCESS	68/2195	0.0142036	0.0126635
GOBP_SECOND_MESSENGER_MEDIATED_SIGNALING	65/2195	0.0142036	0.0126635
GOBP_CELL_CHEMOTAXIS	65/2195	0.0153341	0.0136714
GOBP_DIVALENT_INORGANIC_CATION_HOMEOSTASIS	98/2195	0.0164616	0.0146767
GOBP_REGULATION_OF_CHEMOTAXIS	50/2195	0.0164616	0.0146767
GOBP_ORGANIC_ACID_BIOSYNTHETIC_PROCESS	65/2195	0.0164616	0.0146767
GOBP_POSITIVE_REGULATION_OF_GLYCOLYTIC_PROCESS	10/2195	0.0164616	0.0146767
GOBP_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION	10/2195	0.0164616	0.0146767
GOBP_MYELOID_CELL_DIFFERENTIATION	80/2195	0.0164616	0.0146767
GOBP_REGULATION_OF_ATP_METABOLIC_PROCESS	25/2195	0.0164616	0.0146767
GOBP_REGULATION_OF_T_CELL_ACTIVATION	71/2195	0.0164616	0.0146767
GOBP_REGULATION_OF_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS	9/2195	0.0185701	0.0165566
GOBP_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS	57/2195	0.0185701	0.0165566
GOBP_ALCOHOL_BIOSYNTHETIC_PROCESS	35/2195	0.0185701	0.0165566
GOBP_REGULATION_OF_INFLAMMATORY_RESPONSE	73/2195	0.0189798	0.0169218
GOBP_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION	31/2195	0.0192365	0.0171507
GOBP_MAINTENANCE_OF_LOCATION	68/2195	0.0198452	0.0176934
GOBP_CALCIUM_MEDIATED_SIGNALING	46/2195	0.0208734	0.0186101
GOBP_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS	79/2195	0.0208734	0.0186101
GOBP_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	47/2195	0.0215098	0.0191775
GOBP_INTEGRIN_MEDIATED_SIGNALING_PATHWAY	29/2195	0.0248228	0.0221313
GOBP_MYELOID_LEUKOCYTE_DIFFERENTIATION	48/2195	0.0248228	0.0221313
GOBP_STEROID_BIOSYNTHETIC_PROCESS	41/2195	0.0249771	0.0222689
GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_EXOGENOUS_PEPTIDE_ANTIGEN	13/2195	0.0249771	0.0222689
GOBP_ACTIN_FILAMENT_ORGANIZATION	88/2195	0.0252925	0.0225501
GOBP_REGULATION_OF_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY	28/2195	0.0274800	0.0245003
GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION	37/2195	0.0283127	0.0252428
GOBP_MONONUCLEAR_CELL_MIGRATION	44/2195	0.0284967	0.0254068
GOBP_ALPHA_BETA_T_CELL_ACTIVATION	38/2195	0.0300062	0.0267527
GOBP_HOMOTYPIC_CELL_CELL_ADHESION	25/2195	0.0304769	0.0271724
GOBP_TEMPERATURE_HOMEOSTASIS	42/2195	0.0304769	0.0271724
GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION	89/2195	0.0304769	0.0271724
GOBP_MATURE_B_CELL_DIFFERENTIATION	13/2195	0.0304769	0.0271724
GOBP_NEURON_APOPTOTIC_PROCESS	52/2195	0.0308275	0.0274849
GOBP_REGULATION_OF_GTPASE_ACTIVITY	70/2195	0.0314716	0.0280591
GOBP_PYRUVATE_METABOLIC_PROCESS	28/2195	0.0330592	0.0294746
GOBP_REGULATION_OF_LEUKOCYTE_MIGRATION	47/2195	0.0330592	0.0294746
GOBP_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	31/2195	0.0344973	0.0307568
GOBP_GAMMA_DELTA_T_CELL_ACTIVATION	9/2195	0.0344973	0.0307568
GOBP_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION	69/2195	0.0344973	0.0307568
GOBP_NEURON_DEATH	71/2195	0.0347478	0.0309801
GOBP_CELLULAR_RESPONSE_TO_CALCIUM_ION	23/2195	0.0358732	0.0319835
GOBP_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN	16/2195	0.0358732	0.0319835
GOBP_REGULATION_OF_PLATELET_ACTIVATION	16/2195	0.0358732	0.0319835
GOBP_REGULATION_OF_AXONOGENESIS	37/2195	0.0360894	0.0321762
GOBP_RECEPTOR_MEDIATED_ENDOCYTOSIS	53/2195	0.0360894	0.0321762
GOBP_REGULATION_OF_LEUKOCYTE_PROLIFERATION	53/2195	0.0360894	0.0321762
GOBP_B_CELL_DIFFERENTIATION	34/2195	0.0360894	0.0321762
GOBP_SMOOTH_MUSCLE_CELL_PROLIFERATION	34/2195	0.0360894	0.0321762
GOBP_MYELOID_LEUKOCYTE_ACTIVATION	50/2195	0.0392968	0.0350359
GOBP_CELL_SUBSTRATE_ADHESION	72/2195	0.0396550	0.0353553
GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS	16/2195	0.0415601	0.0370537
GOBP_UNSATURATED_FATTY_ACID_BIOSYNTHETIC_PROCESS	16/2195	0.0415601	0.0370537
GOBP_REGULATION_OF_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY	32/2195	0.0428243	0.0381809
GOBP_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS	73/2195	0.0439075	0.0391466
GOBP_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT	83/2195	0.0439075	0.0391466
GOBP_REGULATION_OF_CARBOHYDRATE_CATABOLIC_PROCESS	17/2195	0.0439075	0.0391466
GOBP_TISSUE_REMODELING	38/2195	0.0439075	0.0391466
GOBP_REGULATION_OF_GLYCOLYTIC_PROCESS	15/2195	0.0439075	0.0391466
GOBP_NEUTROPHIL_EXTRAVASATION	7/2195	0.0439075	0.0391466
GOBP_PEPTIDE_ANTIGEN_ASSEMBLY_WITH_MHC_PROTEIN_COMPLEX	7/2195	0.0439075	0.0391466
GOBP_REGULATION_OF_NEUROGENESIS	71/2195	0.0439753	0.0392071
GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_OR_POLYSACCHARIDE_ANTIGEN_VIA_MHC_CLASS_II	11/2195	0.0439753	0.0392071
GOBP_LEUKOTRIENE_METABOLIC_PROCESS	11/2195	0.0439753	0.0392071
GOBP_LEUKOCYTE_CHEMOTAXIS	49/2195	0.0439753	0.0392071
GOBP_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS	66/2195	0.0449920	0.0401135
GOBP_POSITIVE_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS	14/2195	0.0456568	0.0407062
GOBP_POSITIVE_REGULATION_OF_CHEMOKINE_PRODUCTION	20/2195	0.0456568	0.0407062
GOBP_TISSUE_MIGRATION	62/2195	0.0456568	0.0407062
GOBP_T_CELL_DIFFERENTIATION	57/2195	0.0456568	0.0407062
GOBP_ADP_METABOLIC_PROCESS	24/2195	0.0456568	0.0407062
GOBP_CARBOHYDRATE_TRANSPORT	35/2195	0.0458426	0.0408720
GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN	17/2195	0.0470266	0.0419275
GOBP_NEGATIVE_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	13/2195	0.0480022	0.0427973
GOBP_ERK1_AND_ERK2_CASCADE	64/2195	0.0480266	0.0428191
GOBP_NONRIBOSOMAL_PEPTIDE_BIOSYNTHETIC_PROCESS	8/2195	0.0495090	0.0441408
GOBP_POSITIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE	8/2195	0.0495090	0.0441408

## [1] 110   9

Reactome

ID	GeneRatio	p.adjust	qvalue
REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP	21/1466	0.0001203	0.0001137
REACTOME_CHOLESTEROL_BIOSYNTHESIS	15/1466	0.0001238	0.0001170
REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF	22/1466	0.0020032	0.0018932
REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	71/1466	0.0151756	0.0143421
REACTOME_RESPONSE_OF_EIF2AK1_HRI_TO_HEME_DEFICIENCY	9/1466	0.0151756	0.0143421
REACTOME_LAMININ_INTERACTIONS	13/1466	0.0269626	0.0254817
REACTOME_RHO_GTPASE_CYCLE	92/1466	0.0380360	0.0359469
REACTOME_CDC42_GTPASE_CYCLE	39/1466	0.0380360	0.0359469

## [1] 8 9

Specific pathways signatures

The oxphos signature

Highlight on the volcano plot of the genes found to be implicated in oxphos + table

gene	log2FoldChange	padj	description
1700066M21Rik	0.7760122	0.0000357	RIKEN cDNA 1700066M21 gene [Source:MGI Symbol;Acc:MGI:1920717]
Ak4	-1.0934896	0.0000000	adenylate kinase 4 [Source:MGI Symbol;Acc:MGI:87979]
Atp5pb	0.3489896	0.0164320	ATP synthase peripheral stalk-membrane subunit b [Source:MGI Symbol;Acc:MGI:1100495]
Atpsckmt	0.7738770	0.0001397	ATP synthase C subunit lysine N-methyltransferase [Source:MGI Symbol;Acc:MGI:1915323]
Bid	0.9662152	0.0000000	BH3 interacting domain death agonist [Source:MGI Symbol;Acc:MGI:108093]
Ccnb1	-0.5864787	0.0000052	cyclin B1 [Source:MGI Symbol;Acc:MGI:88302]
Cdk1	-1.1516056	0.0000000	cyclin-dependent kinase 1 [Source:MGI Symbol;Acc:MGI:88351]
Chchd10	2.1496037	0.0000000	coiled-coil-helix-coiled-coil-helix domain containing 10 [Source:MGI Symbol;Acc:MGI:2143558]
Coa6	0.6399467	0.0033147	cytochrome c oxidase assembly factor 6 [Source:MGI Symbol;Acc:MGI:1915142]
Coq9	0.5637524	0.0000185	coenzyme Q9 [Source:MGI Symbol;Acc:MGI:1915164]
Cox4i1	-0.3426376	0.0249665	cytochrome c oxidase subunit 4I1 [Source:MGI Symbol;Acc:MGI:88473]
Cox4i2	-3.8917569	0.0002489	cytochrome c oxidase subunit 4I2 [Source:MGI Symbol;Acc:MGI:2135755]
Cox5a	-0.3174744	0.0291051	cytochrome c oxidase subunit 5A [Source:MGI Symbol;Acc:MGI:88474]
Cox6a2	5.3257345	0.0000000	cytochrome c oxidase subunit 6A2 [Source:MGI Symbol;Acc:MGI:104649]
Cox7a1	-1.4141922	0.0041042	cytochrome c oxidase subunit 7A1 [Source:MGI Symbol;Acc:MGI:1316714]
Cox7a2	-0.9244949	0.0000000	cytochrome c oxidase subunit 7A2 [Source:MGI Symbol;Acc:MGI:1316715]
Cox7a2l	0.3600131	0.0036882	cytochrome c oxidase subunit 7A2 like [Source:MGI Symbol;Acc:MGI:106015]
Cox7b	-0.3257134	0.0196115	cytochrome c oxidase subunit 7B [Source:MGI Symbol;Acc:MGI:1913392]
Cox8a	-0.4335115	0.0011514	cytochrome c oxidase subunit 8A [Source:MGI Symbol;Acc:MGI:105959]
Cyc1	0.5325911	0.0006311	cytochrome c-1 [Source:MGI Symbol;Acc:MGI:1913695]
Dld	0.8010380	0.0000000	dihydrolipoamide dehydrogenase [Source:MGI Symbol;Acc:MGI:107450]
Dnajc15	1.4008090	0.0000000	DnaJ heat shock protein family (Hsp40) member C15 [Source:MGI Symbol;Acc:MGI:1913398]
Fxn	0.5279482	0.0052317	frataxin [Source:MGI Symbol;Acc:MGI:1096879]
Macroh2a1	-0.7760994	0.0000000	macroH2A.1 histone [Source:MGI Symbol;Acc:MGI:1349392]
Mlxipl	-4.8379245	0.0002656	MLX interacting protein-like [Source:MGI Symbol;Acc:MGI:1927999]
Msh2	0.3360493	0.0162811	mutS homolog 2 [Source:MGI Symbol;Acc:MGI:101816]
mt-Cytb	0.7362155	0.0000633	mitochondrially encoded cytochrome b [Source:MGI Symbol;Acc:MGI:102501]
Mtch2	-0.4261732	0.0011588	mitochondrial carrier 2 [Source:MGI Symbol;Acc:MGI:1929260]
Ndufa13	-0.7426656	0.0000002	NADH:ubiquinone oxidoreductase subunit A13 [Source:MGI Symbol;Acc:MGI:1914434]
Ndufa2	0.6702846	0.0000311	NADH:ubiquinone oxidoreductase subunit A2 [Source:MGI Symbol;Acc:MGI:1343103]
Ndufb8	-0.6653651	0.0003593	NADH:ubiquinone oxidoreductase subunit B8 [Source:MGI Symbol;Acc:MGI:1914514]
Ndufc1	0.3598763	0.0464003	NADH:ubiquinone oxidoreductase subunit C1 [Source:MGI Symbol;Acc:MGI:1913627]
Ndufs1	0.4069742	0.0159663	NADH:ubiquinone oxidoreductase core subunit S1 [Source:MGI Symbol;Acc:MGI:2443241]
Ndufs3	0.4565267	0.0014823	NADH:ubiquinone oxidoreductase core subunit S3 [Source:MGI Symbol;Acc:MGI:1915599]
Ndufs5	0.4404621	0.0413439	NADH:ubiquinone oxidoreductase core subunit S5 [Source:MGI Symbol;Acc:MGI:1890889]
Ndufs8	0.3486683	0.0427632	NADH:ubiquinone oxidoreductase core subunit S8 [Source:MGI Symbol;Acc:MGI:2385079]
Ndufv1	0.5371159	0.0003021	NADH:ubiquinone oxidoreductase core subunit V1 [Source:MGI Symbol;Acc:MGI:107851]
Ndufv2	0.3756694	0.0119498	NADH:ubiquinone oxidoreductase core subunit V2 [Source:MGI Symbol;Acc:MGI:1920150]
Ndufv3	-0.4057194	0.0010873	NADH:ubiquinone oxidoreductase core subunit V3 [Source:MGI Symbol;Acc:MGI:1890894]
Nupr1	3.8610012	0.0000000	nuclear protein transcription regulator 1 [Source:MGI Symbol;Acc:MGI:1891834]
Rhoa	0.4320101	0.0002089	ras homolog family member A [Source:MGI Symbol;Acc:MGI:1096342]
Sdhaf2	0.5211079	0.0011438	succinate dehydrogenase complex assembly factor 2 [Source:MGI Symbol;Acc:MGI:1913322]
Sdhd	-0.4140277	0.0050897	succinate dehydrogenase complex, subunit D, integral membrane protein [Source:MGI Symbol;Acc:MGI:1914175]
Shmt2	1.3728711	0.0000000	serine hydroxymethyltransferase 2 (mitochondrial) [Source:MGI Symbol;Acc:MGI:1277989]
Slc25a23	-1.0869440	0.0000001	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 [Source:MGI Symbol;Acc:MGI:1914222]
Slc25a33	1.2239753	0.0000000	solute carrier family 25, member 33 [Source:MGI Symbol;Acc:MGI:1917806]
Tefm	0.9472543	0.0000004	transcription elongation factor, mitochondrial [Source:MGI Symbol;Acc:MGI:1915800]
Tnf	-0.4493040	0.0213785	tumor necrosis factor [Source:MGI Symbol;Acc:MGI:104798]
Uqcc3	0.7342383	0.0000025	ubiquinol-cytochrome c reductase complex assembly factor 3 [Source:MGI Symbol;Acc:MGI:2147553]
Uqcrb	-0.4465303	0.0141058	ubiquinol-cytochrome c reductase binding protein [Source:MGI Symbol;Acc:MGI:1914780]
Uqcrc1	0.4425436	0.0041157	ubiquinol-cytochrome c reductase core protein 1 [Source:MGI Symbol;Acc:MGI:107876]
Uqcrc2	0.2780693	0.0391466	ubiquinol cytochrome c reductase core protein 2 [Source:MGI Symbol;Acc:MGI:1914253]
Uqcrfs1	-0.3677989	0.0136283	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 [Source:MGI Symbol;Acc:MGI:1913944]
Uqcrh	-1.9810039	0.0000000	ubiquinol-cytochrome c reductase hinge protein [Source:MGI Symbol;Acc:MGI:1913826]
Uqcrq	0.8912318	0.0000000	ubiquinol-cytochrome c reductase, complex III subunit VII [Source:MGI Symbol;Acc:MGI:107807]

GSEA on filtered terms from GO, Reactome, Hallmark

The glycolytic process

Highlight on the volcano plot of the genes found to be implicated in oxphos + table

gene	log2FoldChange	padj	description
Adpgk	0.4734952	0.0064508	ADP-dependent glucokinase [Source:MGI Symbol;Acc:MGI:1919391]
Aldoa	-0.4299506	0.0005551	aldolase A, fructose-bisphosphate [Source:MGI Symbol;Acc:MGI:87994]
Aldoc	-3.1681380	0.0000000	aldolase C, fructose-bisphosphate [Source:MGI Symbol;Acc:MGI:101863]
App	1.8053584	0.0001617	amyloid beta (A4) precursor protein [Source:MGI Symbol;Acc:MGI:88059]
Arl2	-0.3653505	0.0411939	ADP-ribosylation factor-like 2 [Source:MGI Symbol;Acc:MGI:1928393]
Cbfa2t3	-3.2411697	0.0005968	CBFA2/RUNX1 translocation partner 3 [Source:MGI Symbol;Acc:MGI:1338013]
Eif6	0.9322629	0.0000000	eukaryotic translation initiation factor 6 [Source:MGI Symbol;Acc:MGI:1196288]
Eno1	-0.4581882	0.0014000	enolase 1, alpha non-neuron [Source:MGI Symbol;Acc:MGI:95393]
Eno2	-1.7183873	0.0000000	enolase 2, gamma neuronal [Source:MGI Symbol;Acc:MGI:95394]
Gale	-1.9234365	0.0000000	galactose-4-epimerase, UDP [Source:MGI Symbol;Acc:MGI:1921496]
Galk1	-1.0579932	0.0000000	galactokinase 1 [Source:MGI Symbol;Acc:MGI:95730]
Galt	-0.7824535	0.0011648	galactose-1-phosphate uridyl transferase [Source:MGI Symbol;Acc:MGI:95638]
Gapdh	-0.7202681	0.0000002	glyceraldehyde-3-phosphate dehydrogenase [Source:MGI Symbol;Acc:MGI:95640]
Gapdhs	-1.0049733	0.0393871	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [Source:MGI Symbol;Acc:MGI:95653]
Gck	-1.7298814	0.0000667	glucokinase [Source:MGI Symbol;Acc:MGI:1270854]
Git1	0.3975993	0.0047473	GIT ArfGAP 1 [Source:MGI Symbol;Acc:MGI:1927140]
Gpi1	-0.5333862	0.0000448	glucose-6-phosphate isomerase 1 [Source:MGI Symbol;Acc:MGI:95797]
Hdac4	1.1816743	0.0000000	histone deacetylase 4 [Source:MGI Symbol;Acc:MGI:3036234]
Hif1a	1.2951858	0.0000000	hypoxia inducible factor 1, alpha subunit [Source:MGI Symbol;Acc:MGI:106918]
Hk1	-1.0348814	0.0000000	hexokinase 1 [Source:MGI Symbol;Acc:MGI:96103]
Htr2a	-2.3294748	0.0008212	5-hydroxytryptamine (serotonin) receptor 2A [Source:MGI Symbol;Acc:MGI:109521]
Ier3	-1.5559821	0.0000000	immediate early response 3 [Source:MGI Symbol;Acc:MGI:104814]
Kat2b	0.4168947	0.0129814	K(lysine) acetyltransferase 2B [Source:MGI Symbol;Acc:MGI:1343094]
Khk	-1.1221658	0.0000000	ketohexokinase [Source:MGI Symbol;Acc:MGI:1096353]
Mlxipl	-4.8379245	0.0002656	MLX interacting protein-like [Source:MGI Symbol;Acc:MGI:1927999]
Mtch2	-0.4261732	0.0011588	mitochondrial carrier 2 [Source:MGI Symbol;Acc:MGI:1929260]
Nupr1	3.8610012	0.0000000	nuclear protein transcription regulator 1 [Source:MGI Symbol;Acc:MGI:1891834]
Ogt	0.4383453	0.0331243	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) [Source:MGI Symbol;Acc:MGI:1339639]
P2rx7	-1.4185347	0.0000448	purinergic receptor P2X, ligand-gated ion channel, 7 [Source:MGI Symbol;Acc:MGI:1339957]
Pfkl	-0.6810711	0.0000036	phosphofructokinase, liver, B-type [Source:MGI Symbol;Acc:MGI:97547]
Pfkm	-1.5673261	0.0000000	phosphofructokinase, muscle [Source:MGI Symbol;Acc:MGI:97548]
Pfkp	-0.9396597	0.0000000	phosphofructokinase, platelet [Source:MGI Symbol;Acc:MGI:1891833]
Pgam1	-0.7307644	0.0000004	phosphoglycerate mutase 1 [Source:MGI Symbol;Acc:MGI:97552]
Pgk1	-1.2025366	0.0000000	phosphoglycerate kinase 1 [Source:MGI Symbol;Acc:MGI:97555]
Pkm	-0.8019957	0.0000000	pyruvate kinase, muscle [Source:MGI Symbol;Acc:MGI:97591]
Ppp2ca	0.3506315	0.0015177	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform [Source:MGI Symbol;Acc:MGI:1321159]
Prkaa1	0.3856019	0.0070116	protein kinase, AMP-activated, alpha 1 catalytic subunit [Source:MGI Symbol;Acc:MGI:2145955]
Prkaa2	3.1369277	0.0057674	protein kinase, AMP-activated, alpha 2 catalytic subunit [Source:MGI Symbol;Acc:MGI:1336173]
Prxl2c	1.4490349	0.0000000	peroxiredoxin like 2C [Source:MGI Symbol;Acc:MGI:1913379]
Psen1	0.3163659	0.0109842	presenilin 1 [Source:MGI Symbol;Acc:MGI:1202717]
Slc2a6	-1.9669537	0.0000000	solute carrier family 2 (facilitated glucose transporter), member 6 [Source:MGI Symbol;Acc:MGI:2443286]
Slc4a4	-2.3285759	0.0291506	solute carrier family 4 (anion exchanger), member 4 [Source:MGI Symbol;Acc:MGI:1927555]
Stat3	-0.6213473	0.0000185	signal transducer and activator of transcription 3 [Source:MGI Symbol;Acc:MGI:103038]
Tigar	0.7190222	0.0000239	Trp53 induced glycolysis regulatory phosphatase [Source:MGI Symbol;Acc:MGI:2442752]
Tpi1	-0.3508434	0.0478321	triosephosphate isomerase 1 [Source:MGI Symbol;Acc:MGI:98797]
Ucp2	-0.8738500	0.0000000	uncoupling protein 2 (mitochondrial, proton carrier) [Source:MGI Symbol;Acc:MGI:109354]
Zbtb7a	0.5138323	0.0000137	zinc finger and BTB domain containing 7a [Source:MGI Symbol;Acc:MGI:1335091]

GSEA on filtered terms from GO, Reactome, Hallmark

## 
## FALSE  TRUE 
##  6802   170

ID	Description	setSize	enrichmentScore	NES	pvalue	p.adjust	qvalue	rank
HALLMARK_GLYCOLYSIS	HALLMARK_GLYCOLYSIS	114	-0.3851379	-1.37242	0.0369721	0.1478884	0.116754	2150

ORA

## 
## FALSE  TRUE 
##  2629    78

ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
GOBP_POSITIVE_REGULATION_OF_GLYCOLYTIC_PROCESS	GOBP_POSITIVE_REGULATION_OF_GLYCOLYTIC_PROCESS	10/78	20/300	0.0150301	0.1052109	0.0949271	Prxl2c/Entpd5/Hif1a/P2rx7/App/Mlxipl/Htr2a/Prkaa2/Slc4a4/Gapdhs	10

The myc signature

Highlight on the volcano plot of the genes found to be implicated in oxphos + table

gene	log2FoldChange	padj	description
Emp1	-3.1496687	0.0000000	epithelial membrane protein 1 [Source:MGI Symbol;Acc:MGI:107941]
Tgm1	-3.1877557	0.0000000	transglutaminase 1, K polypeptide [Source:MGI Symbol;Acc:MGI:98730]
Acss2	-3.0618636	0.0000000	acyl-CoA synthetase short-chain family member 2 [Source:MGI Symbol;Acc:MGI:1890410]
Mettl1	1.9270748	0.0000000	methyltransferase like 1 [Source:MGI Symbol;Acc:MGI:1339986]
Sord	-1.9141737	0.0000000	sorbitol dehydrogenase [Source:MGI Symbol;Acc:MGI:98266]
Ptrh2	1.8232091	0.0000000	peptidyl-tRNA hydrolase 2 [Source:MGI Symbol;Acc:MGI:2444848]
Farsb	1.4337968	0.0000000	phenylalanyl-tRNA synthetase, beta subunit [Source:MGI Symbol;Acc:MGI:1346035]
Pfkm	-1.5673261	0.0000000	phosphofructokinase, muscle [Source:MGI Symbol;Acc:MGI:97548]
Atp2b4	-1.5445844	0.0000000	ATPase, Ca++ transporting, plasma membrane 4 [Source:MGI Symbol;Acc:MGI:88111]
Fgf11	-3.9699044	0.0000000	fibroblast growth factor 11 [Source:MGI Symbol;Acc:MGI:109167]
Ciart	1.6318635	0.0000000	circadian associated repressor of transcription [Source:MGI Symbol;Acc:MGI:2684975]
Ddx10	1.0083366	0.0000000	DEAD box helicase 10 [Source:MGI Symbol;Acc:MGI:1924841]
Taf4b	1.2505871	0.0000000	TATA-box binding protein associated factor 4b [Source:MGI Symbol;Acc:MGI:2152345]
Wdr74	1.2594859	0.0000000	WD repeat domain 74 [Source:MGI Symbol;Acc:MGI:2147427]
Als2cl	-1.1652979	0.0000000	ALS2 C-terminal like [Source:MGI Symbol;Acc:MGI:2447532]
Smtn	-2.4962998	0.0000000	smoothelin [Source:MGI Symbol;Acc:MGI:1354727]
Sorl1	-1.6069430	0.0000000	sortilin-related receptor, LDLR class A repeats-containing [Source:MGI Symbol;Acc:MGI:1202296]
Nop2	1.1273069	0.0000000	NOP2 nucleolar protein [Source:MGI Symbol;Acc:MGI:107891]
Plekhg2	-1.0967184	0.0000000	pleckstrin homology domain containing, family G (with RhoGef domain) member 2 [Source:MGI Symbol;Acc:MGI:2141874]
Tmem97	-1.1491966	0.0000000	transmembrane protein 97 [Source:MGI Symbol;Acc:MGI:1916321]
Ubiad1	1.1222497	0.0000000	UbiA prenyltransferase domain containing 1 [Source:MGI Symbol;Acc:MGI:1918957]
Ddx28	1.0327054	0.0000000	DEAD box helicase 28 [Source:MGI Symbol;Acc:MGI:1919236]
Tcof1	0.8170795	0.0000000	treacle ribosome biogenesis factor 1 [Source:MGI Symbol;Acc:MGI:892003]
Utp20	1.1358903	0.0000000	UTP20 small subunit processome component [Source:MGI Symbol;Acc:MGI:1917933]
Mknk1	0.9474897	0.0000000	MAP kinase-interacting serine/threonine kinase 1 [Source:MGI Symbol;Acc:MGI:894316]
Wsb1	-0.8583915	0.0000000	WD repeat and SOCS box-containing 1 [Source:MGI Symbol;Acc:MGI:1926139]
Lsg1	0.8869362	0.0000000	large 60S subunit nuclear export GTPase 1 [Source:MGI Symbol;Acc:MGI:107236]
Cflar	-1.0475096	0.0000000	CASP8 and FADD-like apoptosis regulator [Source:MGI Symbol;Acc:MGI:1336166]
Erbb3	-1.1937641	0.0000000	erb-b2 receptor tyrosine kinase 3 [Source:MGI Symbol;Acc:MGI:95411]
Ddah2	-2.2902351	0.0000000	dimethylarginine dimethylaminohydrolase 2 [Source:MGI Symbol;Acc:MGI:1859016]
Flnb	-1.1993260	0.0000000	filamin, beta [Source:MGI Symbol;Acc:MGI:2446089]
Dkc1	1.0018518	0.0000000	dyskeratosis congenita 1, dyskerin [Source:MGI Symbol;Acc:MGI:1861727]
Imp4	0.8661539	0.0000000	IMP4, U3 small nucleolar ribonucleoprotein [Source:MGI Symbol;Acc:MGI:106572]
Mybbp1a	0.9816541	0.0000000	MYB binding protein (P160) 1a [Source:MGI Symbol;Acc:MGI:106181]
Ipo4	0.9677200	0.0000000	importin 4 [Source:MGI Symbol;Acc:MGI:1923001]
Vmp1	0.8496348	0.0000000	vacuole membrane protein 1 [Source:MGI Symbol;Acc:MGI:1923159]
Gpatch4	1.1174249	0.0000000	G patch domain containing 4 [Source:MGI Symbol;Acc:MGI:1913864]
Ncl	0.6644353	0.0000000	nucleolin [Source:MGI Symbol;Acc:MGI:97286]
Bid	0.9662152	0.0000000	BH3 interacting domain death agonist [Source:MGI Symbol;Acc:MGI:108093]
Srm	0.9779976	0.0000000	spermidine synthase [Source:MGI Symbol;Acc:MGI:102690]
Ypel3	0.9931970	0.0000000	yippee like 3 [Source:MGI Symbol;Acc:MGI:1913340]
Mical1	-0.8236975	0.0000000	microtubule associated monooxygenase, calponin and LIM domain containing 1 [Source:MGI Symbol;Acc:MGI:2385847]
Runx1	-1.5466996	0.0000000	runt related transcription factor 1 [Source:MGI Symbol;Acc:MGI:99852]
Flad1	0.8404286	0.0000000	flavin adenine dinucleotide synthetase 1 [Source:MGI Symbol;Acc:MGI:2443030]
Hspd1	0.8461482	0.0000000	heat shock protein 1 (chaperonin) [Source:MGI Symbol;Acc:MGI:96242]
Xpo5	0.8717351	0.0000001	exportin 5 [Source:MGI Symbol;Acc:MGI:1913789]
Pmm2	0.7122271	0.0000002	phosphomannomutase 2 [Source:MGI Symbol;Acc:MGI:1859214]
Fam168a	-0.7068709	0.0000002	family with sequence similarity 168, member A [Source:MGI Symbol;Acc:MGI:2442372]
Scfd2	0.9042615	0.0000003	Sec1 family domain containing 2 [Source:MGI Symbol;Acc:MGI:2443446]
Dusp22	-0.9814901	0.0000006	dual specificity phosphatase 22 [Source:MGI Symbol;Acc:MGI:1915926]
Nop56	0.7841447	0.0000008	NOP56 ribonucleoprotein [Source:MGI Symbol;Acc:MGI:1914384]
Prr5	-1.3905581	0.0000008	proline rich 5 (renal) [Source:MGI Symbol;Acc:MGI:1924714]
Ssh3	-1.0015832	0.0000012	slingshot protein phosphatase 3 [Source:MGI Symbol;Acc:MGI:2683546]
Rcl1	0.7953739	0.0000012	RNA terminal phosphate cyclase-like 1 [Source:MGI Symbol;Acc:MGI:1913275]
Paics	-0.6409491	0.0000013	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase [Source:MGI Symbol;Acc:MGI:1914304]
Utp25	0.7150993	0.0000033	UTP25 small subunit processome component [Source:MGI Symbol;Acc:MGI:2138080]
Nfkb2	0.5904101	0.0000054	nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 [Source:MGI Symbol;Acc:MGI:1099800]
Fam193b	-0.6538335	0.0000099	family with sequence similarity 193, member B [Source:MGI Symbol;Acc:MGI:2385851]
Lamc2	-2.2687475	0.0000149	laminin, gamma 2 [Source:MGI Symbol;Acc:MGI:99913]
Gnl3	0.5592179	0.0000165	guanine nucleotide binding protein-like 3 (nucleolar) [Source:MGI Symbol;Acc:MGI:1353651]
Utp4	0.5820015	0.0000185	UTP4 small subunit processome component [Source:MGI Symbol;Acc:MGI:1096573]
Trmt1	0.5719820	0.0000211	tRNA methyltransferase 1 [Source:MGI Symbol;Acc:MGI:1289155]
Ccng2	-1.9899729	0.0000247	cyclin G2 [Source:MGI Symbol;Acc:MGI:1095734]
Dhrs1	-0.6301070	0.0000479	dehydrogenase/reductase (SDR family) member 1 [Source:MGI Symbol;Acc:MGI:1196314]
Ercc1	0.6552681	0.0000599	excision repair cross-complementing rodent repair deficiency, complementation group 1 [Source:MGI Symbol;Acc:MGI:95412]
Nolc1	0.6601334	0.0000738	nucleolar and coiled-body phosphoprotein 1 [Source:MGI Symbol;Acc:MGI:1918019]
Ccdc86	0.7820110	0.0000763	coiled-coil domain containing 86 [Source:MGI Symbol;Acc:MGI:1277220]
Ddx18	0.5674005	0.0001048	DEAD box helicase 18 [Source:MGI Symbol;Acc:MGI:1914192]
Dcaf4	-0.6967061	0.0001116	DDB1 and CUL4 associated factor 4 [Source:MGI Symbol;Acc:MGI:1921078]
Sfxn4	1.2115653	0.0001527	sideroflexin 4 [Source:MGI Symbol;Acc:MGI:2137680]
Nol6	0.6223380	0.0001594	nucleolar protein family 6 (RNA-associated) [Source:MGI Symbol;Acc:MGI:2140151]
Kics2	0.6794121	0.0001657	KICSTOR subunit 2 [Source:MGI Symbol;Acc:MGI:2670984]
Supv3l1	0.6353839	0.0001949	suppressor of var1, 3-like 1 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:2441711]
Slc12a8	1.0020921	0.0002131	solute carrier family 12 (potassium/chloride transporters), member 8 [Source:MGI Symbol;Acc:MGI:2443672]
Nop16	0.6407413	0.0002536	NOP16 nucleolar protein [Source:MGI Symbol;Acc:MGI:107862]
Dgka	-0.4601907	0.0003354	diacylglycerol kinase, alpha [Source:MGI Symbol;Acc:MGI:102952]
Rhbdf1	-1.9726761	0.0004753	rhomboid 5 homolog 1 [Source:MGI Symbol;Acc:MGI:104328]
Bend3	0.7571042	0.0011079	BEN domain containing 3 [Source:MGI Symbol;Acc:MGI:2677212]
Eef1akmt4	1.1661329	0.0015900	EEF1A lysine methyltransferase 4 [Source:MGI Symbol;Acc:MGI:5903914]
Mtmr11	-2.1352633	0.0019487	myotubularin related protein 11 [Source:MGI Symbol;Acc:MGI:2652817]
Ltbp2	-4.3506142	0.0026454	latent transforming growth factor beta binding protein 2 [Source:MGI Symbol;Acc:MGI:99502]
Triobp	-0.3819363	0.0027221	TRIO and F-actin binding protein [Source:MGI Symbol;Acc:MGI:1349410]
Rpp40	0.8519141	0.0034443	ribonuclease P 40 subunit [Source:MGI Symbol;Acc:MGI:1346084]
Ahnak	0.5162983	0.0048042	AHNAK nucleoprotein (desmoyokin) [Source:MGI Symbol;Acc:MGI:1316648]
Atic	0.3783632	0.0066502	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [Source:MGI Symbol;Acc:MGI:1351352]
Plau	-1.8899868	0.0072663	plasminogen activator, urokinase [Source:MGI Symbol;Acc:MGI:97611]
Hspa1a	-4.0590855	0.0074547	heat shock protein 1A [Source:MGI Symbol;Acc:MGI:96244]
Smurf1	0.4244919	0.0127536	SMAD specific E3 ubiquitin protein ligase 1 [Source:MGI Symbol;Acc:MGI:1923038]
Dph1	0.4987930	0.0168050	diphthamide biosynthesis 1 [Source:MGI Symbol;Acc:MGI:2151233]
Rabepk	-0.4345660	0.0176667	Rab9 effector protein with kelch motifs [Source:MGI Symbol;Acc:MGI:2139530]
Gprc5a	-1.4963526	0.0181858	G protein-coupled receptor, family C, group 5, member A [Source:MGI Symbol;Acc:MGI:1891250]
Tuba1a	-0.4114319	0.0202142	tubulin, alpha 1A [Source:MGI Symbol;Acc:MGI:98869]
Dusp2	-0.9407257	0.0458130	dual specificity phosphatase 2 [Source:MGI Symbol;Acc:MGI:101911]
Cgn	-4.0659168	0.0460173	cingulin [Source:MGI Symbol;Acc:MGI:1927237]

Pattern search in data

Slcxxx transporters

gene	log2FoldChange	padj	description
Slc10a3	1.3272526	0.0000000	solute carrier family 10 (sodium/bile acid cotransporter family), member 3 [Source:MGI Symbol;Acc:MGI:95048]
Slc10a7	0.7727925	0.0000001	solute carrier family 10 (sodium/bile acid cotransporter family), member 7 [Source:MGI Symbol;Acc:MGI:1924025]
Slc11a2	-0.6558965	0.0000020	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 [Source:MGI Symbol;Acc:MGI:1345279]
Slc12a2	0.5855368	0.0000146	solute carrier family 12, member 2 [Source:MGI Symbol;Acc:MGI:101924]
Slc12a6	-0.3439601	0.0375410	solute carrier family 12, member 6 [Source:MGI Symbol;Acc:MGI:2135960]
Slc12a7	-0.6772575	0.0005605	solute carrier family 12, member 7 [Source:MGI Symbol;Acc:MGI:1342283]
Slc12a8	1.0020921	0.0002131	solute carrier family 12 (potassium/chloride transporters), member 8 [Source:MGI Symbol;Acc:MGI:2443672]
Slc12a9	-0.4272017	0.0408831	solute carrier family 12 (potassium/chloride transporters), member 9 [Source:MGI Symbol;Acc:MGI:1933532]
Slc13a3	-2.8606764	0.0099823	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 [Source:MGI Symbol;Acc:MGI:2149635]
Slc14a1	-4.3711331	0.0000000	solute carrier family 14 (urea transporter), member 1 [Source:MGI Symbol;Acc:MGI:1351654]
Slc15a1	-5.0940528	0.0000000	solute carrier family 15 (oligopeptide transporter), member 1 [Source:MGI Symbol;Acc:MGI:1861376]
Slc15a2	-1.3998787	0.0328805	solute carrier family 15 (H+/peptide transporter), member 2 [Source:MGI Symbol;Acc:MGI:1890457]
Slc15a3	-1.5699401	0.0000056	solute carrier family 15, member 3 [Source:MGI Symbol;Acc:MGI:1929691]
Slc16a1	0.3437910	0.0276993	solute carrier family 16 (monocarboxylic acid transporters), member 1 [Source:MGI Symbol;Acc:MGI:106013]
Slc16a3	-1.3104331	0.0000000	solute carrier family 16 (monocarboxylic acid transporters), member 3 [Source:MGI Symbol;Acc:MGI:1933438]
Slc16a4	-1.4371569	0.0353102	solute carrier family 16 (monocarboxylic acid transporters), member 4 [Source:MGI Symbol;Acc:MGI:2385183]
Slc17a7	-0.8332790	0.0360313	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 [Source:MGI Symbol;Acc:MGI:1920211]
Slc17a8	-1.1445038	0.0282709	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 [Source:MGI Symbol;Acc:MGI:3039629]
Slc17a9	-0.7838368	0.0000016	solute carrier family 17, member 9 [Source:MGI Symbol;Acc:MGI:1919107]
Slc1a1	-5.3009735	0.0086272	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 [Source:MGI Symbol;Acc:MGI:105083]
Slc1a2	-2.6430983	0.0000000	solute carrier family 1 (glial high affinity glutamate transporter), member 2 [Source:MGI Symbol;Acc:MGI:101931]
Slc1a4	2.5220787	0.0000000	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 [Source:MGI Symbol;Acc:MGI:2135601]
Slc1a5	0.7101692	0.0000000	solute carrier family 1 (neutral amino acid transporter), member 5 [Source:MGI Symbol;Acc:MGI:105305]
Slc20a1	0.4063330	0.0090301	solute carrier family 20, member 1 [Source:MGI Symbol;Acc:MGI:108392]
Slc22a15	-0.8605500	0.0004438	solute carrier family 22 (organic anion/cation transporter), member 15 [Source:MGI Symbol;Acc:MGI:3607704]
Slc22a17	-2.0544400	0.0000007	solute carrier family 22 (organic cation transporter), member 17 [Source:MGI Symbol;Acc:MGI:1926225]
Slc23a2	0.3585350	0.0102129	solute carrier family 23 (nucleobase transporters), member 2 [Source:MGI Symbol;Acc:MGI:1859682]
Slc24a3	1.4249301	0.0000038	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 [Source:MGI Symbol;Acc:MGI:2137513]
Slc24a5	-1.8358563	0.0126162	solute carrier family 24, member 5 [Source:MGI Symbol;Acc:MGI:2677271]
Slc25a1	-1.7655179	0.0000000	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 [Source:MGI Symbol;Acc:MGI:1345283]
Slc25a10	-1.2352295	0.0000000	solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 [Source:MGI Symbol;Acc:MGI:1353497]
Slc25a12	0.6561441	0.0000005	solute carrier family 25 (mitochondrial carrier, Aralar), member 12 [Source:MGI Symbol;Acc:MGI:1926080]
Slc25a13	-0.8343217	0.0001822	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 [Source:MGI Symbol;Acc:MGI:1354721]
Slc25a15	0.8503196	0.0000000	solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15 [Source:MGI Symbol;Acc:MGI:1342274]
Slc25a16	0.5000528	0.0034495	solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16 [Source:MGI Symbol;Acc:MGI:1920382]
Slc25a20	0.7237088	0.0000004	solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 [Source:MGI Symbol;Acc:MGI:1928738]
Slc25a22	0.5410579	0.0000736	solute carrier family 25 (mitochondrial carrier, glutamate), member 22 [Source:MGI Symbol;Acc:MGI:1915517]
Slc25a23	-1.0869440	0.0000001	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 [Source:MGI Symbol;Acc:MGI:1914222]
Slc25a24	0.6281013	0.0000007	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24 [Source:MGI Symbol;Acc:MGI:1917160]
Slc25a26	0.9033687	0.0005920	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26 [Source:MGI Symbol;Acc:MGI:1914832]
Slc25a28	-0.4140519	0.0495053	solute carrier family 25, member 28 [Source:MGI Symbol;Acc:MGI:2180509]
Slc25a29	-1.2110655	0.0365723	solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29 [Source:MGI Symbol;Acc:MGI:2444911]
Slc25a30	-0.6798868	0.0000723	solute carrier family 25, member 30 [Source:MGI Symbol;Acc:MGI:1914804]
Slc25a33	1.2239753	0.0000000	solute carrier family 25, member 33 [Source:MGI Symbol;Acc:MGI:1917806]
Slc25a38	0.5173423	0.0078595	solute carrier family 25, member 38 [Source:MGI Symbol;Acc:MGI:2384782]
Slc25a4	-0.6332772	0.0000000	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 [Source:MGI Symbol;Acc:MGI:1353495]
Slc25a40	0.3419097	0.0131815	solute carrier family 25, member 40 [Source:MGI Symbol;Acc:MGI:2442486]
Slc25a44	0.6043962	0.0000891	solute carrier family 25, member 44 [Source:MGI Symbol;Acc:MGI:2444391]
Slc25a46	0.3301174	0.0087313	solute carrier family 25, member 46 [Source:MGI Symbol;Acc:MGI:1914703]
Slc25a5	-1.5226570	0.0000000	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 [Source:MGI Symbol;Acc:MGI:1353496]
Slc25a51	1.0789570	0.0000000	solute carrier family 25, member 51 [Source:MGI Symbol;Acc:MGI:2684984]
Slc26a11	-1.4136626	0.0000000	solute carrier family 26, member 11 [Source:MGI Symbol;Acc:MGI:2444589]
Slc27a1	-1.4445309	0.0000000	solute carrier family 27 (fatty acid transporter), member 1 [Source:MGI Symbol;Acc:MGI:1347098]
Slc27a6	-4.5237778	0.0012570	solute carrier family 27 (fatty acid transporter), member 6 [Source:MGI Symbol;Acc:MGI:3036230]
Slc28a2	-0.7962408	0.0000223	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Source:MGI Symbol;Acc:MGI:1913105]
Slc28a2b	-2.7291844	0.0000000	solute carrier family 28 member 2b [Source:MGI Symbol;Acc:MGI:3702173]
Slc29a1	0.3180878	0.0240215	solute carrier family 29 (nucleoside transporters), member 1 [Source:MGI Symbol;Acc:MGI:1927073]
Slc29a3	0.7076904	0.0000347	solute carrier family 29 (nucleoside transporters), member 3 [Source:MGI Symbol;Acc:MGI:1918529]
Slc29a4	-2.6092781	0.0000345	solute carrier family 29 (nucleoside transporters), member 4 [Source:MGI Symbol;Acc:MGI:2385330]
Slc2a1	-0.3243542	0.0275535	solute carrier family 2 (facilitated glucose transporter), member 1 [Source:MGI Symbol;Acc:MGI:95755]
Slc2a2	2.7218764	0.0483250	solute carrier family 2 (facilitated glucose transporter), member 2 [Source:MGI Symbol;Acc:MGI:1095438]
Slc2a3	-2.6399868	0.0000000	solute carrier family 2 (facilitated glucose transporter), member 3 [Source:MGI Symbol;Acc:MGI:95757]
Slc2a4	-2.8985075	0.0168390	solute carrier family 2 (facilitated glucose transporter), member 4 [Source:MGI Symbol;Acc:MGI:95758]
Slc2a4rg-ps	-0.7404864	0.0021495	Slc2a4 regulator, pseudogene [Source:MGI Symbol;Acc:MGI:3651388]
Slc2a5	5.2883022	0.0007654	solute carrier family 2 (facilitated glucose transporter), member 5 [Source:MGI Symbol;Acc:MGI:1928369]
Slc2a6	-1.9669537	0.0000000	solute carrier family 2 (facilitated glucose transporter), member 6 [Source:MGI Symbol;Acc:MGI:2443286]
Slc2a8	-1.0449811	0.0000012	solute carrier family 2, (facilitated glucose transporter), member 8 [Source:MGI Symbol;Acc:MGI:1860103]
Slc2a9	-1.1445865	0.0000000	solute carrier family 2 (facilitated glucose transporter), member 9 [Source:MGI Symbol;Acc:MGI:2152844]
Slc30a2	-1.0093378	0.0000036	solute carrier family 30 (zinc transporter), member 2 [Source:MGI Symbol;Acc:MGI:106637]
Slc30a6	0.5191305	0.0041348	solute carrier family 30 (zinc transporter), member 6 [Source:MGI Symbol;Acc:MGI:2386741]
Slc30a7	-0.7340821	0.0000000	solute carrier family 30 (zinc transporter), member 7 [Source:MGI Symbol;Acc:MGI:1913750]
Slc30a9	-0.4707012	0.0001905	solute carrier family 30 (zinc transporter), member 9 [Source:MGI Symbol;Acc:MGI:1923690]
Slc31a1	-1.1448185	0.0000000	solute carrier family 31, member 1 [Source:MGI Symbol;Acc:MGI:1333843]
Slc35a1	0.4272772	0.0129488	solute carrier family 35 (CMP-sialic acid transporter), member 1 [Source:MGI Symbol;Acc:MGI:1345622]
Slc35a2	-0.6966878	0.0000002	solute carrier family 35 (UDP-galactose transporter), member A2 [Source:MGI Symbol;Acc:MGI:1345297]
Slc35a4	0.4463924	0.0098637	solute carrier family 35, member A4 [Source:MGI Symbol;Acc:MGI:1915093]
Slc35b1	0.6316125	0.0018720	solute carrier family 35, member B1 [Source:MGI Symbol;Acc:MGI:1343133]
Slc35b2	-0.8838625	0.0000000	solute carrier family 35, member B2 [Source:MGI Symbol;Acc:MGI:1921086]
Slc35b3	1.1375800	0.0000000	solute carrier family 35, member B3 [Source:MGI Symbol;Acc:MGI:1913978]
Slc35b4	0.5985159	0.0000286	solute carrier family 35, member B4 [Source:MGI Symbol;Acc:MGI:1931249]
Slc35c1	-0.4993699	0.0002621	solute carrier family 35, member C1 [Source:MGI Symbol;Acc:MGI:2443301]
Slc35d2	1.0787948	0.0000000	solute carrier family 35, member D2 [Source:MGI Symbol;Acc:MGI:1917734]
Slc35d3	-1.4882762	0.0000000	solute carrier family 35, member D3 [Source:MGI Symbol;Acc:MGI:1923407]
Slc35e3	0.8042712	0.0001124	solute carrier family 35, member E3 [Source:MGI Symbol;Acc:MGI:2448489]
Slc35e4	-0.6756747	0.0386563	solute carrier family 35, member E4 [Source:MGI Symbol;Acc:MGI:2144150]
Slc35f5	-0.7192395	0.0024784	solute carrier family 35, member F5 [Source:MGI Symbol;Acc:MGI:1921400]
Slc36a1	-0.3922563	0.0326994	solute carrier family 36 (proton/amino acid symporter), member 1 [Source:MGI Symbol;Acc:MGI:2445299]
Slc36a3os	-1.5510091	0.0000947	solute carrier family 36 (proton/amino acid symporter), member 3, opposite strand [Source:MGI Symbol;Acc:MGI:3651340]
Slc37a1	-0.6521863	0.0003524	solute carrier family 37 (glycerol-3-phosphate transporter), member 1 [Source:MGI Symbol;Acc:MGI:2446181]
Slc37a2	-0.8157979	0.0054171	solute carrier family 37 (glycerol-3-phosphate transporter), member 2 [Source:MGI Symbol;Acc:MGI:1929693]
Slc37a3	-0.8580720	0.0000986	solute carrier family 37 (glycerol-3-phosphate transporter), member 3 [Source:MGI Symbol;Acc:MGI:1919394]
Slc37a4	-1.2924409	0.0000000	solute carrier family 37 (glucose-6-phosphate transporter), member 4 [Source:MGI Symbol;Acc:MGI:1316650]
Slc38a1	1.0784495	0.0000000	solute carrier family 38, member 1 [Source:MGI Symbol;Acc:MGI:2145895]
Slc38a11	-4.7785962	0.0058363	solute carrier family 38, member 11 [Source:MGI Symbol;Acc:MGI:2443383]
Slc38a2	0.6309382	0.0006392	solute carrier family 38, member 2 [Source:MGI Symbol;Acc:MGI:1915010]
Slc38a3	-5.5447002	0.0012732	solute carrier family 38, member 3 [Source:MGI Symbol;Acc:MGI:1923507]
Slc38a7	2.2145401	0.0000000	solute carrier family 38, member 7 [Source:MGI Symbol;Acc:MGI:2679005]
Slc39a10	-2.3493697	0.0000000	solute carrier family 39 (zinc transporter), member 10 [Source:MGI Symbol;Acc:MGI:1914515]
Slc39a11	0.4641243	0.0027936	solute carrier family 39 (metal ion transporter), member 11 [Source:MGI Symbol;Acc:MGI:1917056]
Slc39a14	-0.4908269	0.0014061	solute carrier family 39 (zinc transporter), member 14 [Source:MGI Symbol;Acc:MGI:2384851]
Slc39a3	1.5500267	0.0000000	solute carrier family 39 (zinc transporter), member 3 [Source:MGI Symbol;Acc:MGI:2147269]
Slc39a8	-0.3905488	0.0236311	solute carrier family 39 (metal ion transporter), member 8 [Source:MGI Symbol;Acc:MGI:1914797]
Slc39a9	0.7565966	0.0000000	solute carrier family 39 (zinc transporter), member 9 [Source:MGI Symbol;Acc:MGI:1914820]
Slc3a2	1.6270692	0.0000000	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 [Source:MGI Symbol;Acc:MGI:96955]
Slc41a1	-0.5531261	0.0006171	solute carrier family 41, member 1 [Source:MGI Symbol;Acc:MGI:2444823]
Slc41a2	-1.9954949	0.0000000	solute carrier family 41, member 2 [Source:MGI Symbol;Acc:MGI:2442940]
Slc43a3	2.0310270	0.0000000	solute carrier family 43, member 3 [Source:MGI Symbol;Acc:MGI:1931054]
Slc48a1	0.6597327	0.0000934	solute carrier family 48 (heme transporter), member 1 [Source:MGI Symbol;Acc:MGI:1914989]
Slc4a1ap	0.3745562	0.0106459	solute carrier family 4 (anion exchanger), member 1, adaptor protein [Source:MGI Symbol;Acc:MGI:1196608]
Slc4a2	0.7002426	0.0000004	solute carrier family 4 (anion exchanger), member 2 [Source:MGI Symbol;Acc:MGI:109351]
Slc4a4	-2.3285759	0.0291506	solute carrier family 4 (anion exchanger), member 4 [Source:MGI Symbol;Acc:MGI:1927555]
Slc4a5	-2.8233783	0.0012507	solute carrier family 4, sodium bicarbonate cotransporter, member 5 [Source:MGI Symbol;Acc:MGI:2443220]
Slc4a7	-1.4953647	0.0000000	solute carrier family 4, sodium bicarbonate cotransporter, member 7 [Source:MGI Symbol;Acc:MGI:2443878]
Slc4a8	-1.9058995	0.0000000	solute carrier family 4 (anion exchanger), member 8 [Source:MGI Symbol;Acc:MGI:1928745]
Slc52a2	0.8794775	0.0000001	solute carrier protein 52, member 2 [Source:MGI Symbol;Acc:MGI:1289288]
Slc52a3	-0.6952197	0.0000792	solute carrier protein family 52, member 3 [Source:MGI Symbol;Acc:MGI:1916948]
Slc5a11	-2.6957867	0.0040635	solute carrier family 5 (sodium/glucose cotransporter), member 11 [Source:MGI Symbol;Acc:MGI:1919316]
Slc5a3	-1.5676192	0.0000000	solute carrier family 5 (inositol transporters), member 3 [Source:MGI Symbol;Acc:MGI:1858226]
Slc66a2	-0.8418121	0.0000387	solute carrier family 66 member 2 [Source:MGI Symbol;Acc:MGI:1914193]
Slc6a19	-2.6083929	0.0000000	solute carrier family 6 (neurotransmitter transporter), member 19 [Source:MGI Symbol;Acc:MGI:1921588]
Slc6a9	3.3901792	0.0000000	solute carrier family 6 (neurotransmitter transporter, glycine), member 9 [Source:MGI Symbol;Acc:MGI:95760]
Slc7a1	1.5639238	0.0000000	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 [Source:MGI Symbol;Acc:MGI:88117]
Slc7a11	4.5421075	0.0000000	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 [Source:MGI Symbol;Acc:MGI:1347355]
Slc7a3	3.0344226	0.0000000	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 [Source:MGI Symbol;Acc:MGI:1100521]
Slc7a4	-1.0605721	0.0078851	solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 [Source:MGI Symbol;Acc:MGI:2146512]
Slc7a5	1.7007402	0.0000000	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 [Source:MGI Symbol;Acc:MGI:1298205]
Slc7a6os	0.3525473	0.0140697	solute carrier family 7, member 6 opposite strand [Source:MGI Symbol;Acc:MGI:1916951]
Slc8a2	-4.5904212	0.0401056	solute carrier family 8 (sodium/calcium exchanger), member 2 [Source:MGI Symbol;Acc:MGI:107996]
Slc8b1	-1.0110415	0.0000018	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 [Source:MGI Symbol;Acc:MGI:2180781]
Slc9a3r2	-1.8434473	0.0023648	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 [Source:MGI Symbol;Acc:MGI:1890662]
Slc9a5	-2.3085685	0.0000000	solute carrier family 9 (sodium/hydrogen exchanger), member 5 [Source:MGI Symbol;Acc:MGI:2685542]
Slc9a6	0.4050384	0.0140882	solute carrier family 9 (sodium/hydrogen exchanger), member 6 [Source:MGI Symbol;Acc:MGI:2443511]
Slc9a9	0.6823560	0.0006338	solute carrier family 9 (sodium/hydrogen exchanger), member 9 [Source:MGI Symbol;Acc:MGI:2679732]
Slco3a1	-0.7747586	0.0000000	solute carrier organic anion transporter family, member 3a1 [Source:MGI Symbol;Acc:MGI:1351867]
Slco5a1	-4.1539351	0.0266312	solute carrier organic anion transporter family, member 5A1 [Source:MGI Symbol;Acc:MGI:2443431]

Mitochondria mention in gene description

gene	log2FoldChange	padj	description
Acaa2	-0.9551231	0.0000000	acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) [Source:MGI Symbol;Acc:MGI:1098623]
Aco2	0.4359586	0.0050425	aconitase 2, mitochondrial [Source:MGI Symbol;Acc:MGI:87880]
Aifm1	-0.7501800	0.0000004	apoptosis-inducing factor, mitochondrion-associated 1 [Source:MGI Symbol;Acc:MGI:1349419]
Aifm2	-0.5455704	0.0144775	apoptosis-inducing factor, mitochondrion-associated 2 [Source:MGI Symbol;Acc:MGI:1918611]
Aldh2	-0.6246235	0.0000217	aldehyde dehydrogenase 2, mitochondrial [Source:MGI Symbol;Acc:MGI:99600]
Atp5a1	0.3593452	0.0126667	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 [Source:MGI Symbol;Acc:MGI:88115]
Atp5b	0.4444880	0.0054968	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit [Source:MGI Symbol;Acc:MGI:107801]
Atp5c1	-0.4730395	0.0005534	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 [Source:MGI Symbol;Acc:MGI:1261437]
Atp5g1	1.1148189	0.0000000	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9) [Source:MGI Symbol;Acc:MGI:107653]
Atp5g3	-0.3607325	0.0272852	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) [Source:MGI Symbol;Acc:MGI:2442035]
Atp5k	-0.9091723	0.0000114	ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit E [Source:MGI Symbol;Acc:MGI:106636]
Atpaf1	0.5203139	0.0036255	ATP synthase mitochondrial F1 complex assembly factor 1 [Source:MGI Symbol;Acc:MGI:2180560]
Bcat2	0.6473152	0.0000005	branched chain aminotransferase 2, mitochondrial [Source:MGI Symbol;Acc:MGI:1276534]
Car5b	-2.7340286	0.0000000	carbonic anhydrase 5b, mitochondrial [Source:MGI Symbol;Acc:MGI:1926249]
Ckmt1	-0.6523058	0.0213253	creatine kinase, mitochondrial 1, ubiquitous [Source:MGI Symbol;Acc:MGI:99441]
Clic4	1.6169240	0.0000000	chloride intracellular channel 4 (mitochondrial) [Source:MGI Symbol;Acc:MGI:1352754]
Clpp	0.5385684	0.0004474	caseinolytic mitochondrial matrix peptidase proteolytic subunit [Source:MGI Symbol;Acc:MGI:1858213]
Clpx	0.4341872	0.0003626	caseinolytic mitochondrial matrix peptidase chaperone subunit [Source:MGI Symbol;Acc:MGI:1346017]
Cluh	0.5110198	0.0004831	clustered mitochondria (cluA/CLU1) homolog [Source:MGI Symbol;Acc:MGI:1921398]
Cmc1	-0.5322571	0.0015204	COX assembly mitochondrial protein 1 [Source:MGI Symbol;Acc:MGI:1915149]
Decr1	0.6682613	0.0000014	2,4-dienoyl CoA reductase 1, mitochondrial [Source:MGI Symbol;Acc:MGI:1914710]
Ears2	1.3691260	0.0000000	glutamyl-tRNA synthetase 2, mitochondrial [Source:MGI Symbol;Acc:MGI:1914667]
Echs1	0.4182121	0.0019499	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial [Source:MGI Symbol;Acc:MGI:2136460]
Gfm1	0.4416229	0.0009390	G elongation factor, mitochondrial 1 [Source:MGI Symbol;Acc:MGI:107339]
Gfm2	0.4445604	0.0006467	G elongation factor, mitochondrial 2 [Source:MGI Symbol;Acc:MGI:2444783]
Gls2	-2.1391724	0.0000000	glutaminase 2 (liver, mitochondrial) [Source:MGI Symbol;Acc:MGI:2143539]
Gpd2	-0.6027938	0.0000003	glycerol phosphate dehydrogenase 2, mitochondrial [Source:MGI Symbol;Acc:MGI:99778]
Grpel1	0.6597476	0.0001300	GrpE-like 1, mitochondrial [Source:MGI Symbol;Acc:MGI:1334417]
Grpel2	0.9869394	0.0000000	GrpE-like 2, mitochondrial [Source:MGI Symbol;Acc:MGI:1334416]
Iars2	0.4132887	0.0022574	isoleucine-tRNA synthetase 2, mitochondrial [Source:MGI Symbol;Acc:MGI:1919586]
Idh2	-0.4465370	0.0014368	isocitrate dehydrogenase 2 (NADP+), mitochondrial [Source:MGI Symbol;Acc:MGI:96414]
Immp1l	0.4814687	0.0275931	IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1913791]
Immt	0.4775035	0.0003439	inner membrane protein, mitochondrial [Source:MGI Symbol;Acc:MGI:1923864]
Lonp1	0.9611996	0.0000000	lon peptidase 1, mitochondrial [Source:MGI Symbol;Acc:MGI:1921392]
Mars2	-0.3451218	0.0387289	methionine-tRNA synthetase 2 (mitochondrial) [Source:MGI Symbol;Acc:MGI:2444136]
Mcat	0.6167150	0.0005216	malonyl CoA:ACP acyltransferase (mitochondrial) [Source:MGI Symbol;Acc:MGI:2388651]
Mcu	0.7142379	0.0000023	mitochondrial calcium uniporter [Source:MGI Symbol;Acc:MGI:3026965]
Mcur1	0.4425286	0.0095945	mitochondrial calcium uniporter regulator 1 [Source:MGI Symbol;Acc:MGI:1923387]
Me2	-1.2753266	0.0000000	malic enzyme 2, NAD(+)-dependent, mitochondrial [Source:MGI Symbol;Acc:MGI:2147351]
Mecr	0.7923092	0.0000649	mitochondrial trans-2-enoyl-CoA reductase [Source:MGI Symbol;Acc:MGI:1349441]
Metap1d	1.0750737	0.0000000	methionyl aminopeptidase type 1D (mitochondrial) [Source:MGI Symbol;Acc:MGI:1913809]
Mgarp	-2.5608898	0.0000000	mitochondria localized glutamic acid rich protein [Source:MGI Symbol;Acc:MGI:1914999]
Micos13	0.5347154	0.0031850	mitochondrial contact site and cristae organizing system subunit 13 [Source:MGI Symbol;Acc:MGI:2442174]
Micu2	0.4872478	0.0001788	mitochondrial calcium uptake 2 [Source:MGI Symbol;Acc:MGI:1915764]
Mief1	0.4013588	0.0022555	mitochondrial elongation factor 1 [Source:MGI Symbol;Acc:MGI:2146020]
Mief2	0.6982455	0.0000230	mitochondrial elongation factor 2 [Source:MGI Symbol;Acc:MGI:2144199]
Mpc1	0.8262940	0.0000569	mitochondrial pyruvate carrier 1 [Source:MGI Symbol;Acc:MGI:1915240]
Mpc2	0.9851654	0.0000000	mitochondrial pyruvate carrier 2 [Source:MGI Symbol;Acc:MGI:1917706]
Mpv17	0.5133903	0.0299904	MpV17 mitochondrial inner membrane protein [Source:MGI Symbol;Acc:MGI:97138]
Mrm2	0.7854998	0.0040564	mitochondrial rRNA methyltransferase 2 [Source:MGI Symbol;Acc:MGI:1915267]
Mrm3	1.6108031	0.0000000	mitochondrial rRNA methyltransferase 3 [Source:MGI Symbol;Acc:MGI:1914640]
Mrpl1	0.6516791	0.0000063	mitochondrial ribosomal protein L1 [Source:MGI Symbol;Acc:MGI:2137202]
Mrpl12	0.5801012	0.0003907	mitochondrial ribosomal protein L12 [Source:MGI Symbol;Acc:MGI:1926273]
Mrpl13	0.4694678	0.0278946	mitochondrial ribosomal protein L13 [Source:MGI Symbol;Acc:MGI:2137218]
Mrpl15	0.5538012	0.0001601	mitochondrial ribosomal protein L15 [Source:MGI Symbol;Acc:MGI:1351639]
Mrpl16	0.7127472	0.0000045	mitochondrial ribosomal protein L16 [Source:MGI Symbol;Acc:MGI:2137219]
Mrpl20	1.1426471	0.0000005	mitochondrial ribosomal protein L20 [Source:MGI Symbol;Acc:MGI:2137221]
Mrpl22	0.3729122	0.0387289	mitochondrial ribosomal protein L22 [Source:MGI Symbol;Acc:MGI:1333794]
Mrpl24	0.8988928	0.0000000	mitochondrial ribosomal protein L24 [Source:MGI Symbol;Acc:MGI:1914957]
Mrpl32	0.3670363	0.0389341	mitochondrial ribosomal protein L32 [Source:MGI Symbol;Acc:MGI:2137226]
Mrpl34	0.4381507	0.0108217	mitochondrial ribosomal protein L34 [Source:MGI Symbol;Acc:MGI:2137227]
Mrpl35	1.1910160	0.0000000	mitochondrial ribosomal protein L35 [Source:MGI Symbol;Acc:MGI:1913473]
Mrpl37	0.4867745	0.0010938	mitochondrial ribosomal protein L37 [Source:MGI Symbol;Acc:MGI:1926268]
Mrpl38	0.5103793	0.0006597	mitochondrial ribosomal protein L38 [Source:MGI Symbol;Acc:MGI:1926269]
Mrpl39	0.7582155	0.0000000	mitochondrial ribosomal protein L39 [Source:MGI Symbol;Acc:MGI:1351620]
Mrpl44	0.5468557	0.0010572	mitochondrial ribosomal protein L44 [Source:MGI Symbol;Acc:MGI:1916413]
Mrpl46	0.9301607	0.0000036	mitochondrial ribosomal protein L46 [Source:MGI Symbol;Acc:MGI:1914558]
Mrpl49	0.8486033	0.0000000	mitochondrial ribosomal protein L49 [Source:MGI Symbol;Acc:MGI:108180]
Mrpl51	0.8120511	0.0000027	mitochondrial ribosomal protein L51 [Source:MGI Symbol;Acc:MGI:1913743]
Mrpl52	0.9345527	0.0000001	mitochondrial ribosomal protein L52 [Source:MGI Symbol;Acc:MGI:1916086]
Mrpl55	0.9146226	0.0000121	mitochondrial ribosomal protein L55 [Source:MGI Symbol;Acc:MGI:1914462]
Mrpl57	0.4814018	0.0017609	mitochondrial ribosomal protein L57 [Source:MGI Symbol;Acc:MGI:1915090]
Mrpl58	0.8839499	0.0000000	mitochondrial ribosomal protein L58 [Source:MGI Symbol;Acc:MGI:1915822]
Mrps10	0.3934038	0.0357250	mitochondrial ribosomal protein S10 [Source:MGI Symbol;Acc:MGI:1928139]
Mrps14	0.9155799	0.0000001	mitochondrial ribosomal protein S14 [Source:MGI Symbol;Acc:MGI:1928141]
Mrps17	0.7082269	0.0000003	mitochondrial ribosomal protein S17 [Source:MGI Symbol;Acc:MGI:1913508]
Mrps18a	0.7074740	0.0000104	mitochondrial ribosomal protein S18A [Source:MGI Symbol;Acc:MGI:1915815]
Mrps18b	0.8604917	0.0000003	mitochondrial ribosomal protein S18B [Source:MGI Symbol;Acc:MGI:1914223]
Mrps18c	0.6130606	0.0248621	mitochondrial ribosomal protein S18C [Source:MGI Symbol;Acc:MGI:1915985]
Mrps2	0.9638881	0.0000000	mitochondrial ribosomal protein S2 [Source:MGI Symbol;Acc:MGI:2153089]
Mrps22	0.9308891	0.0000001	mitochondrial ribosomal protein S22 [Source:MGI Symbol;Acc:MGI:1928137]
Mrps24	0.4392034	0.0134288	mitochondrial ribosomal protein S24 [Source:MGI Symbol;Acc:MGI:1928142]
Mrps26	0.5754311	0.0001584	mitochondrial ribosomal protein S26 [Source:MGI Symbol;Acc:MGI:1333830]
Mrps28	0.8039814	0.0000148	mitochondrial ribosomal protein S28 [Source:MGI Symbol;Acc:MGI:1913480]
Mrps31	0.9653545	0.0000001	mitochondrial ribosomal protein S31 [Source:MGI Symbol;Acc:MGI:1913153]
Mrps5	0.5141060	0.0004713	mitochondrial ribosomal protein S5 [Source:MGI Symbol;Acc:MGI:1924971]
Mrps6	0.5212900	0.0240897	mitochondrial ribosomal protein S6 [Source:MGI Symbol;Acc:MGI:2153111]
Mrrf	0.9586699	0.0000000	mitochondrial ribosome recycling factor [Source:MGI Symbol;Acc:MGI:1915121]
Mss51	-1.4696795	0.0002575	MSS51 mitochondrial translational activator [Source:MGI Symbol;Acc:MGI:1922093]
Msto1	-0.3925561	0.0102490	misato 1, mitochondrial distribution and morphology regulator [Source:MGI Symbol;Acc:MGI:2385175]
mt-Cytb	0.7362155	0.0000633	mitochondrially encoded cytochrome b [Source:MGI Symbol;Acc:MGI:102501]
Mtarc2	0.2828941	0.0480976	mitochondrial amidoxime reducing component 2 [Source:MGI Symbol;Acc:MGI:1914497]
Mtch1	-0.9257171	0.0000000	mitochondrial carrier 1 [Source:MGI Symbol;Acc:MGI:1929261]
Mtch2	-0.4261732	0.0011588	mitochondrial carrier 2 [Source:MGI Symbol;Acc:MGI:1929260]
Mterf3	0.9277654	0.0000000	mitochondrial transcription termination factor 3 [Source:MGI Symbol;Acc:MGI:1913660]
Mterf4	0.3820499	0.0347419	mitochondrial transcription termination factor 4 [Source:MGI Symbol;Acc:MGI:1918355]
Mtfmt	-0.4597867	0.0045195	mitochondrial methionyl-tRNA formyltransferase [Source:MGI Symbol;Acc:MGI:1916856]
Mtfr1	0.9052520	0.0000000	mitochondrial fission regulator 1 [Source:MGI Symbol;Acc:MGI:1914722]
Mtfr1l	0.8822730	0.0000000	mitochondrial fission regulator 1-like [Source:MGI Symbol;Acc:MGI:1924074]
Mtfr2	-0.8579038	0.0000304	mitochondrial fission regulator 2 [Source:MGI Symbol;Acc:MGI:1919054]
Mtg1	0.7734630	0.0000005	mitochondrial ribosome-associated GTPase 1 [Source:MGI Symbol;Acc:MGI:2685015]
Mtg2	0.8257217	0.0000034	mitochondrial ribosome associated GTPase 2 [Source:MGI Symbol;Acc:MGI:106565]
Mtif2	0.6153472	0.0000148	mitochondrial translational initiation factor 2 [Source:MGI Symbol;Acc:MGI:1924034]
Mtpap	0.5958172	0.0000141	mitochondrial poly(A) polymerase [Source:MGI Symbol;Acc:MGI:1914690]
Mtrf1	0.5078737	0.0431338	mitochondrial translational release factor 1 [Source:MGI Symbol;Acc:MGI:2384815]
Mtrfr	1.0206204	0.0000048	mitochondrial translation release factor in rescue [Source:MGI Symbol;Acc:MGI:1919900]
Mul1	0.3632292	0.0324422	mitochondrial ubiquitin ligase activator of NFKB 1 [Source:MGI Symbol;Acc:MGI:1915600]
Nadk2	-0.8394495	0.0000110	NAD kinase 2, mitochondrial [Source:MGI Symbol;Acc:MGI:1915896]
Ndufa4	-0.9249425	0.0000000	Ndufa4, mitochondrial complex associated [Source:MGI Symbol;Acc:MGI:107686]
Nt5m	0.7314453	0.0000535	5’,3’-nucleotidase, mitochondrial [Source:MGI Symbol;Acc:MGI:1917127]
Oxsm	0.4932018	0.0056981	3-oxoacyl-ACP synthase, mitochondrial [Source:MGI Symbol;Acc:MGI:1918397]
Pck2	0.9288534	0.0000000	phosphoenolpyruvate carboxykinase 2 (mitochondrial) [Source:MGI Symbol;Acc:MGI:1860456]
Polrmt	0.4191897	0.0040463	polymerase (RNA) mitochondrial (DNA directed) [Source:MGI Symbol;Acc:MGI:1915843]
Rars2	1.6012957	0.0000000	arginyl-tRNA synthetase 2, mitochondrial [Source:MGI Symbol;Acc:MGI:1923596]
Shmt2	1.3728711	0.0000000	serine hydroxymethyltransferase 2 (mitochondrial) [Source:MGI Symbol;Acc:MGI:1277989]
Slc25a1	-1.7655179	0.0000000	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 [Source:MGI Symbol;Acc:MGI:1345283]
Slc25a10	-1.2352295	0.0000000	solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 [Source:MGI Symbol;Acc:MGI:1353497]
Slc25a12	0.6561441	0.0000005	solute carrier family 25 (mitochondrial carrier, Aralar), member 12 [Source:MGI Symbol;Acc:MGI:1926080]
Slc25a13	-0.8343217	0.0001822	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 [Source:MGI Symbol;Acc:MGI:1354721]
Slc25a15	0.8503196	0.0000000	solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15 [Source:MGI Symbol;Acc:MGI:1342274]
Slc25a16	0.5000528	0.0034495	solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16 [Source:MGI Symbol;Acc:MGI:1920382]
Slc25a20	0.7237088	0.0000004	solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 [Source:MGI Symbol;Acc:MGI:1928738]
Slc25a22	0.5410579	0.0000736	solute carrier family 25 (mitochondrial carrier, glutamate), member 22 [Source:MGI Symbol;Acc:MGI:1915517]
Slc25a23	-1.0869440	0.0000001	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 [Source:MGI Symbol;Acc:MGI:1914222]
Slc25a24	0.6281013	0.0000007	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24 [Source:MGI Symbol;Acc:MGI:1917160]
Slc25a26	0.9033687	0.0005920	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26 [Source:MGI Symbol;Acc:MGI:1914832]
Slc25a29	-1.2110655	0.0365723	solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29 [Source:MGI Symbol;Acc:MGI:2444911]
Slc25a4	-0.6332772	0.0000000	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 [Source:MGI Symbol;Acc:MGI:1353495]
Slc25a5	-1.5226570	0.0000000	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 [Source:MGI Symbol;Acc:MGI:1353496]
Taco1	0.6846252	0.0024780	translational activator of mitochondrially encoded cytochrome c oxidase I [Source:MGI Symbol;Acc:MGI:1917457]
Tefm	0.9472543	0.0000004	transcription elongation factor, mitochondrial [Source:MGI Symbol;Acc:MGI:1915800]
Tfam	0.5264095	0.0000244	transcription factor A, mitochondrial [Source:MGI Symbol;Acc:MGI:107810]
Tfb1m	0.9319333	0.0000001	transcription factor B1, mitochondrial [Source:MGI Symbol;Acc:MGI:2146851]
Timm10	1.1016785	0.0000000	translocase of inner mitochondrial membrane 10 [Source:MGI Symbol;Acc:MGI:1353429]
Timm13	0.5079654	0.0008720	translocase of inner mitochondrial membrane 13 [Source:MGI Symbol;Acc:MGI:1353432]
Timm17a	0.6626551	0.0000404	translocase of inner mitochondrial membrane 17a [Source:MGI Symbol;Acc:MGI:1343131]
Timm21	0.3955789	0.0235638	translocase of inner mitochondrial membrane 21 [Source:MGI Symbol;Acc:MGI:1920595]
Timm22	0.7086218	0.0000015	translocase of inner mitochondrial membrane 22 [Source:MGI Symbol;Acc:MGI:1929742]
Timm23	0.6211246	0.0001260	translocase of inner mitochondrial membrane 23 [Source:MGI Symbol;Acc:MGI:1858317]
Timm29	0.3246959	0.0176516	translocase of inner mitochondrial membrane 29 [Source:MGI Symbol;Acc:MGI:1917023]
Timm44	0.2926062	0.0234966	translocase of inner mitochondrial membrane 44 [Source:MGI Symbol;Acc:MGI:1343262]
Timm50	0.9600814	0.0000000	translocase of inner mitochondrial membrane 50 [Source:MGI Symbol;Acc:MGI:1913775]
Timm8a1	0.6470090	0.0111425	translocase of inner mitochondrial membrane 8A1 [Source:MGI Symbol;Acc:MGI:1353433]
Timm8b	-0.5251897	0.0015813	translocase of inner mitochondrial membrane 8B [Source:MGI Symbol;Acc:MGI:1353424]
Timm9	0.6737270	0.0000164	translocase of inner mitochondrial membrane 9 [Source:MGI Symbol;Acc:MGI:1353436]
Tk2	1.0801457	0.0000000	thymidine kinase 2, mitochondrial [Source:MGI Symbol;Acc:MGI:1913266]
Tomm5	0.3920338	0.0479489	translocase of outer mitochondrial membrane 5 [Source:MGI Symbol;Acc:MGI:1915762]
Tsfm	0.3965722	0.0170216	Ts translation elongation factor, mitochondrial [Source:MGI Symbol;Acc:MGI:1913649]
Tst	-1.7642216	0.0024784	thiosulfate sulfurtransferase, mitochondrial [Source:MGI Symbol;Acc:MGI:98852]
Tusc2	1.3741976	0.0000000	tumor suppressor 2, mitochondrial calcium regulator [Source:MGI Symbol;Acc:MGI:1931086]
Ucp2	-0.8738500	0.0000000	uncoupling protein 2 (mitochondrial, proton carrier) [Source:MGI Symbol;Acc:MGI:109354]
Vars2	-0.4418199	0.0034171	valyl-tRNA synthetase 2, mitochondrial [Source:MGI Symbol;Acc:MGI:1916165]
Xpnpep3	0.8425571	0.0000000	X-prolyl aminopeptidase 3, mitochondrial [Source:MGI Symbol;Acc:MGI:2445217]
Yars2	0.4734760	0.0084785	tyrosyl-tRNA synthetase 2 (mitochondrial) [Source:MGI Symbol;Acc:MGI:1917370]